Evidence map›Paper›PMID 30642905›Full record

ArticleInfection and immunity2019

Induction of Inflammatory Responses in Splenocytes by Exosomes Released from Intestinal Epithelial Cells following

Yang Wang, Yujuan Shen, Hua Liu, Jianhai Yin, Xin-Tian Zhang, Ai-Yu Gong, Xiqiang Chen, Siyi Chen, Nicholas W Mathy, Jianping Cao and 1 more

Open access · bronzeAbstract read
In one paragraph

Article in Infection and immunity, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
3.1field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 33 citations in OpenAlex.

  1. Prevalence ofFrontiers in cellular and infection microbiology · 2021
    Pooled it
  2. Article
  3. Review
  4. Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  5. Review
  6. Article
  7. Early immune and host cell responses toFrontiers in parasitology · 2023
    Article
  8. Review
  9. Review
  10. Review
  11. Review
  12. Article
  13. Review
  14. mFrontiers in immunology · 2021
    Article
  15. Review
  16. Article
  17. Exosomes in Sepsis.Frontiers in immunology · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 2 countries.

Yang WangDepartment of Medical Microbiology and Immunology, Creighton University School of Medicine, Omaha, Nebraska, USA.
Yujuan ShenNational Institute of Parasitic Diseases, Chinese Center for Disease Control and Prevention, Shanghai, China.
Hua LiuNational Institute of Parasitic Diseases, Chinese Center for Disease Control and Prevention, Shanghai, China.
Jianhai YinNational Institute of Parasitic Diseases, Chinese Center for Disease Control and Prevention, Shanghai, China.
Xin-Tian ZhangDepartment of Medical Microbiology and Immunology, Creighton University School of Medicine, Omaha, Nebraska, USA.
Ai-Yu GongDepartment of Medical Microbiology and Immunology, Creighton University School of Medicine, Omaha, Nebraska, USA.
Xiqiang ChenDepartment of Medical Microbiology and Immunology, Creighton University School of Medicine, Omaha, Nebraska, USA.
Siyi ChenCreighton University School of Pharmacy and Health Professions, Omaha, Nebraska, USA.
Nicholas W MathyDepartment of Medical Microbiology and Immunology, Creighton University School of Medicine, Omaha, Nebraska, USA.
Jianping CaoNational Institute of Parasitic Diseases, Chinese Center for Disease Control and Prevention, Shanghai, China.
Xian-Ming ChenDepartment of Medical Microbiology and Immunology, Creighton University School of Medicine, Omaha, Nebraska, USA xianmingchen@creighton.edu.
Creighton University · USNational Institute for Parasitic Diseases · CN

Funding

Molecular Basis of Intestinal CryptosporidiosisR01AI116323 · NIAID · RUSH UNIVERSITY MEDICAL CENTER · PI CHEN, XIAN-MING · 2015 to 2025
$4.2M
LincRNAs in Mucosal Defense to AIDS Opportunistic Pathogen CryptosporidiumR01AI136877 · NIAID · RUSH UNIVERSITY MEDICAL CENTER · PI CHEN, XIAN-MING · 2018 to 2022
$1.9M
Epithelial exosomes and TLR-mediated mucosal defenseU01AI095532 · NIAID · CREIGHTON UNIVERSITY · PI CHEN, XIAN-MING · 2011 to 2015
$1.5M
NIAID NIH HHS R01 AI116323NIAID NIH HHS R01 AI136877NIAID NIH HHS U01 AI095532
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsCryptosporidiosisCryptosporidium parvumEpithelial CellsExosomesFemaleHigh Mobility Group ProteinsHumansIntestinesLiverMaleMiceMice, Inbred C57BLNF-kappa BSpleenHigh Mobility Group ProteinsNF-kappa BcryptosporidiosisCryptosporidiumexosomesintestinal epitheliumNF-κBparasitic infectionsplenocytes

Identifiers

PMID30642905
PMCPMC6434132
OpenAlexW2909422995

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.