Evidence map›Paper›PMID 30642904›Full record

ArticleInfection and immunity2019

Moderately Neutralizing Epitopes in Nonfunctional Regions Dominate the Antibody Response to

Nichole D Salinas, May M Paing, Jagat Adhikari, Michael L Gross, Niraj Tolia

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Infection and immunity, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 10 citations in OpenAlex.

  1. Malaria: past, present, and future.Signal transduction and targeted therapy · 2025
    Review
  2. Cells · 2024
    Review
  3. Review
  4. Article
  5. Article
  6. Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Nichole D Salinas *Laboratory of Malaria Immunology and Vaccinology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA.
May M Paing *Department of Molecular Microbiology, Washington University School of Medicine, Saint Louis, Missouri, USA.
Jagat AdhikariDepartment of Chemistry, Washington University, Saint Louis, Missouri, USA.
Michael L GrossDepartment of Chemistry, Washington University, Saint Louis, Missouri, USA.
Niraj ToliaLaboratory of Malaria Immunology and Vaccinology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA niraj.tolia@nih.gov.ORCID 0000-0002-2689-1337
Washington University in St. Louis · USNational Institutes of Health · US

Funding

Viral Discovery in Rheumatoid ArthritisP30AR048335 · NIAMS · WASHINGTON UNIVERSITY · PI YOKOYAMA, WAYNE M. · 2001 to 2015
$8.9M
Mechanisms of effective antibody neutralization of malaria parasitesZIAAI001236 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI TOLIA, NIRAJ · 2018 to 2025
$6.6M
Structural vaccinology for malariaZIAAI001253 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI TOLIA, NIRAJ · 2019 to 2025
$4.9M
ELUCIDATING & DISRUPTING PLASMODIUM RECEPTOR-LIGAND INTERACTIONSR56AI080792 · NIAID · WASHINGTON UNIVERSITY · PI TOLIA, NIRAJ H. · 2015 to 2015
$381k
NIAID NIH HHS HHSN272201400018CNIAID NIH HHS R56 AI080792NIAMS NIH HHS P30 AR048335
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Amino Acid SequenceAnimalsAntibodies, NeutralizingAntibodies, ProtozoanAntibody FormationCarrier ProteinsEpitope MappingEpitopesHumansMalaria, FalciparumMaleMembrane ProteinsMice, Inbred BALB CPlasmodium falciparumProtein DomainsProtozoan ProteinsAntibodies, NeutralizingAntibodies, ProtozoanCarrier ProteinsEBA140 protein, Plasmodium falciparumEpitopesMembrane ProteinsProtozoan Proteinsantibody functionepitopeimmunogen designmalariaPlasmodium falciparumstructural vaccinologythree-dimensional structurevaccines

Identifiers

PMID30642904
PMCPMC6434137
OpenAlexW2910701490

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.