Evidence map›Paper›PMID 30642892›Full record

ArticleThe Journal of cell biology2019

ATM is activated by ATP depletion and modulates mitochondrial function through NRF1.

Hei-Man Chow, Aifang Cheng, Xuan Song, Mavis R Swerdel, Ronald P Hart, Karl Herrup

Open access · bronzeAbstract read
In one paragraph

Article in The Journal of cell biology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers.

0numbers the graph read from it
0cells of the map it votes in
46citing papers in PubMed
3.0field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

46 citing papers in PubMed, 79 citations in OpenAlex.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 3 countries.

Hei-Man ChowDivision of Life Science and The State Key Laboratory of Molecular Neuroscience, Hong Kong University of Science and Technology, Hong Kong heimanchow@ust.hk.
Aifang ChengDivision of Life Science and The State Key Laboratory of Molecular Neuroscience, Hong Kong University of Science and Technology, Hong Kong.ORCID 0000-0002-5022-418X
Xuan SongDivision of Life Science and The State Key Laboratory of Molecular Neuroscience, Hong Kong University of Science and Technology, Hong Kong.
Mavis R SwerdelDepartment of Cell Biology and Neuroscience, Rutgers University, New Brunswick, NJ.
Ronald P HartDepartment of Cell Biology and Neuroscience, Rutgers University, New Brunswick, NJ.
Karl HerrupDivision of Life Science and The State Key Laboratory of Molecular Neuroscience, Hong Kong University of Science and Technology, Hong Kong herrup@ust.hk.ORCID 0000-0001-7786-5844
Hong Kong University of Science and Technology · HKRutgers, The State University of New Jersey · US

Funding

Mechanism of Gene Environment Interactions in Alzheimer's DiseaseR01ES026057 · NIEHS · NORTHEAST OHIO MEDICAL UNIVERSITY · PI RICHARDSON, JASON R · 2016 to 2020
$2.4M
NIEHS NIH HHS R01 ES026057
6 · The paper itself

Abstract

Ataxia-telangiectasia (A-T) is an autosomal recessive disease caused by mutation of the

Indexed as

Adenosine TriphosphateAnimalsAtaxia TelangiectasiaAtaxia Telangiectasia Mutated ProteinsCells, CulturedHumansMiceMitochondriaNuclear Respiratory Factor 1Purkinje CellsAdenosine TriphosphateAtaxia Telangiectasia Mutated ProteinsATM protein, humanAtm protein, mouseNRF1 protein, humanNrf1 protein, mouseNuclear Respiratory Factor 1

Identifiers

PMID30642892
PMCPMC6400560
OpenAlexW2950152058

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.