ArticleBMJ case reports2019
Fulminant Guillain-Barré syndrome in a patient with systemic lupus erythematosus.
Article in BMJ case reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 3 of them syntheses that pooled it.
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Who cites it
10 citing papers in PubMed, 3 syntheses or guidelines pooled it, 17 citations in OpenAlex.
- Qualitative evaluation of pharmacological strategy for connective tissue diseases with Guillain-Barré syndrome: a systematic review.Frontiers in immunology · 2026Pooled it
- A multidimensional analysis of neuropsychiatric lupus: clinical, biological and imaging insights from systematic evidence.Frontiers in immunology · 2026Pooled it
- Trauma-Related Guillain-Barré Syndrome: Systematic Review of an Emerging Concept.Frontiers in neurology · 2020Pooled it
- From Nerve to Autoimmunity: Acute Guillain-Barré Syndrome in a 4-Year-Old with Early-Onset Pediatric Systemic Lupus Erythematosus.Open access rheumatology : research and reviews · 2026Article
- Immunoglobulin unresponsive Guillain-Barré syndrome: rinse or repeat? A systematic review.BMJ neurology open · 2025Article
- Systemic lupus erythematosus complicated by severe Guillain-Barré syndrome: case report and literature review.Frontiers in immunology · 2025Review
- Case Report: Guillain-Barré Syndrome as Primary Presentation of Systemic Lupus Erythematosus (SLE-GBS) in a Teenage Girl.Frontiers in pediatrics · 2022Article
- Systemic lupus erythematosus and critical illness polyneuropathy.Reumatologia · 2021Article
- Antiganglioside antibodies and paraneoplastic neuromuscular junction disorder?eNeurologicalSci · 2020Article
- Acute motor-sensory axonal neuropathy associated with systemic lupus erythematosus.Proceedings (Baylor University. Medical Center) · 2019Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A 45-year-old man with a history of systemic lupus erythematosus presented with progressive weakness and areflexia. Electromyogram revealed reduced motor and sensory amplitudes without demyelinating features. He was clinically diagnosed with the acute motor and sensory axonal neuropathy variant of Guillain-Barré syndrome. Despite intravenous immunoglobulin therapy, he deteriorated with loss of all voluntary motor function and cranial nerve reflexes. Concomitant investigations revealed class V lupus nephritis. Therapy was initiated with plasma exchange, glucocorticoids and further immunosuppression, with gradual neurological recovery. We present the first documented case of fulminant Guillain-Barré syndrome as a neuropsychiatric manifestation of systemic lupus erythematosus, highlighting how immune-mediated polyneuropathy via diffuse deafferentation may mimic the outward appearance of brain death. While glucocorticoids are not indicated in idiopathic Guillain-Barré, when this neurological disorder is a consequence of systemic lupus erythematosus, immunomodulatory treatment should be initiated to prevent neurological deterioration.
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