Evidence map›Paper›PMID 30642721›Full record

ArticleDiagnostic microbiology and infectious disease2019

Dual rapid test for HIV and syphilis: A laboratory evaluation of the diagnostic accuracy of the Standard Q HIV/Syphilis Combo Test.

Claire C Bristow, Silver Keith Vargas Rivera, Lourdes B Ramos Cordova, Luz Jazmín Qquellon Palacios, Kelika A Konda, Jeffrey D Klausner

Open access · greenAbstract readEvaluation Study
In one paragraph

Article in Diagnostic microbiology and infectious disease, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.1field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 3 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Claire C BristowDivision of Infectious Diseases and Global Public Health, Department of Medicine, University of California San Diego, La Jolla, CA, USA. Electronic address: cbristow@ucsd.edu.
Silver Keith Vargas RiveraUniversidad Peruana Cayetano Heredia, Lima, Peru.
Lourdes B Ramos CordovaUniversidad Peruana Cayetano Heredia, Lima, Peru.
Luz Jazmín Qquellon PalaciosUniversidad Peruana Cayetano Heredia, Lima, Peru.
Kelika A KondaDivision of Infectious Diseases, Department of Medicine, University of California Los Angeles, Los Angeles, CA, USA.
Jeffrey D KlausnerDivision of Infectious Diseases, Department of Medicine, University of California Los Angeles, Los Angeles, CA, USA; Department of Epidemiology, Fielding School of Public Health, University of California Los Angeles, Los Angeles, CA, USA.
Universidad Peruana Cayetano Heredia · PEUniversity of California, Los Angeles · USUniversity of California, San Diego · US

Funding

UC San Diego Clinical and Translational Research InstituteUL1TR001442 · NCATS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI FIRESTEIN, GARY S, HOGARTH, MICHAEL · 2015 to 2024
$88.3M
VirologyP30AI036214 · NIAID · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Maile Ann Young Karris · 1994 to 2026
$78.4M
UCLA Rapid, Relevant, Rigorous Implementation Science HubP30MH058107 · NIMH · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI RAPHAEL J LANDOVITZ · 1997 to 2026
$53.5M
Virology CoreP30AI028697 · NIAID · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI CHEN, IRVIN S.Y. · 1991 to 2018
$39.9M
HOPE Training GrantT32AI007384 · NIAID · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Sara Gianella Weibel, Scott L Letendre · 1990 to 2026
$9.7M
Molecular epidemiology of HIV and Neisseria gonorrhoeae in the context of drug resistanceK01AI136725 · NIAID · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI BRISTOW, CLAIRE C · 2018 to 2022
$689k
NCATS NIH HHS UL1 TR001442NIAID NIH HHS K01 AI136725NIAID NIH HHS P30 AI028697NIAID NIH HHS P30 AI036214NIAID NIH HHS T32 AI007384NIMH NIH HHS P30 MH058107
6 · The paper itself

Abstract

We evaluated the Standard Q HIV/Syphilis Combo Test (SD Biosensor, South Korea), a dual rapid test using stored sera (N = 400) in a laboratory setting in Lima, Peru. The sensitivity and specificity for HIV antibody detection was 100.0% (95% CI: 98.2-100.0%) and 99.5% (95% CI: 97.2-100.0%), respectively. For treponemal antibody detection the sensitivity and specificity was 97.5% (95%CI:94.3-99.2%) and 100.0% (95%CI:98.2-100.0%), respectively.

Indexed as

Antibodies, BacterialClinical Laboratory TechniquesDiagnostic Tests, RoutineHIV AntibodiesHIV InfectionsHumansImmunoassayPeruSensitivity and SpecificitySyphilisTime FactorsAntibodies, BacterialHIV AntibodiesDiagnosisDual testHIVRapid testTreponema pallidum

Identifiers

PMID30642721
PMCPMC6462422
OpenAlexW2901308822

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.