Evidence map›Paper›PMID 30642583›Full record

ArticleVeterinary microbiology2019

Identification and characterization of epizootic hemorrhagic disease virus serotype 6 in cattle co-infected with bluetongue virus in Trinidad, West Indies.

Tamiko Brown-Joseph, Paulina Rajko-Nenow, Hayley Hicks, Nikita Sahadeo, Lara E Harrup, Christine V Carrington, Carrie Batten, Christopher A L Oura

Open access · hybridAbstract read
In one paragraph

Article in Veterinary microbiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
1.9field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.

  1. Pooled it
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  13. Randomly primed, strand-switching, MinION-based sequencing for the detection and characterization of cultured RNA viruses.Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Tamiko Brown-JosephDepartment of Pre-Clinical Sciences, Faculty of Medical Sciences, The University of the West Indies, St. Augustine, Trinidad, West Indies. Electronic address: Tamikobj@gmail.com.
Paulina Rajko-NenowNon-vesicular reference laboratory, The Pirbright Institute, Woking, Surrey, GU24 0NF, UK.
Hayley HicksNon-vesicular reference laboratory, The Pirbright Institute, Woking, Surrey, GU24 0NF, UK.
Nikita SahadeoDepartment of Pre-Clinical Sciences, Faculty of Medical Sciences, The University of the West Indies, St. Augustine, Trinidad, West Indies.
Lara E HarrupEntomology Group, The Pirbright Institute, Woking, Surrey, GU24 0NF, UK.
Christine V CarringtonDepartment of Pre-Clinical Sciences, Faculty of Medical Sciences, The University of the West Indies, St. Augustine, Trinidad, West Indies.
Carrie BattenNon-vesicular reference laboratory, The Pirbright Institute, Woking, Surrey, GU24 0NF, UK.
Christopher A L OuraSchool of Veterinary Medicine, Faculty of Medical Sciences, The University of theWest Indies, St. Augustine, Trinidad, West Indies.
The Pirbright Institute · GBUniversity of the West Indies · TT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Epizootic hemorrhagic disease virus (EHDV) is an economically important virus that can cause severe clinical disease in deer and to a lesser extent cattle. This study set out to determine and characterize which EHDV serotypes were circulating in Trinidad. Serum and whole blood samples were collected monthly for six months from a cohort of cattle imported to Trinidad from the USA. Results revealed that all the cattle seroconverted to EHDV within six months of their arrival, with EHDV RNA being detected in the samples just prior to antibodies, as expected. Serotyping assays revealed that a single serotype (EHDV-6) was circulating in the cattle. Sequencing of the surface viral protein (VP2) of EHDV-6, followed by phylogenetic analysis, revealed that the Trinidad EHDV-6 strain was closely related to EHDV-6 viruses found in Guadeloupe (2010), Martinique (2010) and USA (2006), with 96-97.2% nucleotide identity. The Trinidad EHDV-6 VP-2 shared 97.2% identity with the Australian EHDV-6 prototype strain, classifying it within the eastern topotype clade. Bayesian coalescent analysis support Australia as the most probable source for the EHDV-6 VP2 sequences in the Americas and Caribbean region and suggests that the they diverged from the Australian prototype strain around 1966 (95% HPD 1941-1979).

Indexed as

AnimalsBluetongueBluetongue virusCapsid ProteinsCattleCattle DiseasesFemaleHemorrhagic Disease Virus, EpizooticMalePhylogenyRNA, ViralSerogroupTrinidad and TobagoCapsid ProteinsRNA, ViralBTV co-circulationcattleCulicoidesEHDV evolution rateEHDV serotypesTrinidad

Identifiers

PMID30642583
PMCPMC6340808
OpenAlexW2904863038

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.