ArticlePsychological medicine2019
Parsing components of auditory predictive coding in schizophrenia using a roving standard mismatch negativity paradigm.
Article in Psychological medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed.
- Reliability of mismatch negativity event-related potentials in a multisite, traveling subjects study.Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology · 2020Trial
- Concurrent Assessment of Sequential Auditory Event-Related Potentials Using an Optimized Paired-Stimulus Local-Global Paradigm.The European journal of neuroscience · 2026Review
- Differing Pattern of Mismatch Negativity Responses in Clinical and Nonclinical Voice Hearers Challenge Predictive Coding Accounts of Psychosis.Biological psychiatry global open science · 2025Article
- Neurophysiological Models in Individuals at Clinical High Risk for Psychosis: Using Translational EEG Paradigms to Forecast Psychosis Risk and Resilience.Advances in neurobiology · 2024Review
- Extended accelerated tDCS and correction of prediction error signalling in Schizophrenia with atypical hallucinations: A case report.Asian journal of psychiatry · 2023Article
- Habituation, Adaptation and Prediction Processes in Neurodevelopmental Disorders: A Comprehensive Review.Brain sciences · 2023Review
- Correlation of motor-auditory cross-modal and auditory unimodal N1 and mismatch responses of schizophrenic patients and normal subjects: an MEG study.Frontiers in psychiatry · 2023Article
- Physical but not virtual presence of others potentiates implicit and explicit learning.Scientific reports · 2022Article
- Unveiling the Associations between EEG Indices and Cognitive Deficits in Schizophrenia-Spectrum Disorders: A Systematic Review.Diagnostics (Basel, Switzerland) · 2022Review
- Electroencephalography and Event-Related Potential Biomarkers in Individuals at Clinical High Risk for Psychosis.Biological psychiatry · 2020Review
- Associations of mismatch negativity with psychotic symptoms and functioning transdiagnostically across psychotic disorders.Journal of abnormal psychology · 2020Article
- Deficits in auditory predictive coding in individuals with the psychosis risk syndrome: Prediction of conversion to psychosis.Journal of abnormal psychology · 2020Article
- Reduced Auditory Mismatch Negativity Reflects Impaired Deviance Detection in Schizophrenia.Schizophrenia bulletin · 2020Article
- Stability of mismatch negativity event-related potentials in a multisite study.International journal of methods in psychiatric research · 2020Article
- A Predictive Coding Perspective on Mismatch Negativity Impairment in Schizophrenia.Frontiers in psychiatry · 2020Review
- Change in the Neural Response to Auditory Deviance Following Cognitive Therapy for Hallucinations in Patients With Schizophrenia.Frontiers in psychiatry · 2020Article
- Making Sense of Mismatch Negativity.Frontiers in psychiatry · 2020Review
- Auditory Mismatch Negativity Under Predictive Coding Framework and Its Role in Psychotic Disorders.Frontiers in psychiatry · 2020Review
- Accelerated tDCS improves corollary discharge deficit & prediction error signalling in schizophrenia: A case report.Brain stimulationArticle
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Authors and funding
7 authors.
Funding
Abstract
backgroundMismatch negativity (MMN) is an event-related potential (ERP) component reflecting auditory predictive coding. Repeated standard tones evoke increasing positivity ('repetition positivity'; RP), reflecting strengthening of the standard's memory trace and the prediction it will recur. Likewise, deviant tones preceded by more standard repetitions evoke greater negativity ('deviant negativity'; DN), reflecting stronger prediction error signaling. These memory trace effects are also evident in MMN difference wave. Here, we assess group differences and test-retest reliability of these indices in schizophrenia patients (SZ) and healthy controls (HC).
methodsElectroencephalography was recorded twice, 2 weeks apart, from 43 SZ and 30 HC, during a roving standard paradigm. We examined ERPs to the third, eighth, and 33rd standards (RP), immediately subsequent deviants (DN), and the corresponding MMN. Memory trace effects were assessed by comparing amplitudes associated with the three standard repetition trains.
resultsCompared with controls, SZ showed reduced MMNs and DNs, but normal RPs. Both groups showed memory trace effects for RP, MMN, and DN, with a trend for attenuated DNs in SZ. Intraclass correlations obtained via this paradigm indicated good-to-moderate reliabilities for overall MMN, DN and RP, but moderate to poor reliabilities for components associated with short, intermediate, and long standard trains, and poor reliability of their memory trace effects.
conclusionMMN deficits in SZ reflected attenuated prediction error signaling (DN), with relatively intact predictive code formation (RP) and memory trace effects. This roving standard MMN paradigm requires additional development/validation to obtain suitable levels of reliability for use in clinical trials.
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