Observational studyBMC research notes2019
A pilot observational study measuring acute sarcopenia in older colorectal surgery patients.
Observational study in BMC research notes, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03858192 (Understanding Acute Sarcopenia), which is not on this map. Cited by 12 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Understanding Acute Sarcopenia: a Time-limited Cohort Study to Characterise Changes in Muscle Mass and Physical Function in Older Adults Following Hospitalisation
Who cites it
12 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- A Systematic Review and Meta-Analysis of Perioperative Muscle Wasting Following Major Abdominal Surgery.Journal of cachexia, sarcopenia and muscle · 2026Pooled it
- Consensus-defined sarcopenia predicts adverse outcomes after elective abdominal surgery: meta-analysis.BJS open · 2023Pooled it
- Review
- Acute Sarcopenia: Mechanisms and Management.Nutrients · 2024Review
- Muscle ultrasound and its application to point-of-care ultrasonography: a narrative review.Annals of medicine · 2023Review
- Physical frailty recovery is slower than mental frailty recovery after non-cardiac surgery in older adult patients.Langenbeck's archives of surgery · 2023Article
- Investigating the impact of fluid status on the ultrasound assessment of muscle quantity and quality in the diagnosis of sarcopenia - a multidimensional cross-sectional study.BMC geriatrics · 2023Article
- Acute Sarcopenia after Elective and Emergency Surgery.Aging and disease · 2022Review
- Muscle Evaluation and Hospital-Associated Disability in Acute Hospitalized Older Adults.The journal of nutrition, health & aging · 2022Observational
- Post-COVID-19 acute sarcopenia: physiopathology and management.Aging clinical and experimental research · 2021Review
- Effect of position and exercise on measurement of muscle quantity and quality: towards a standardised pragmatic protocol for clinical practice.BMC sports science, medicine & rehabilitation · 2021Article
- Protocol for understanding acute sarcopenia: a cohort study to characterise changes in muscle quantity and physical function in older adults following hospitalisation.BMC geriatrics · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
objectiveTo explore variability in acute changes in muscle mass and function in older patients undergoing elective colorectal surgery, as well as feasibility of measures, in order to refine study processes to inform the protocol for a larger study.
resultsResults are presented for seven participants recruited to this pilot study. It is possible to perform serial measurements of bilateral anterior thigh thickness (BATT) and handgrip strength prior to, within 24 h of surgery, and 1 week postoperatively. Gait speed can be reliably measured preoperatively and at 1 week postoperatively. In this pilot study, BATT and gait speed declined at 1 week postoperatively (median BATT 4.17 cm, 3.47 cm, p = 0.028; median gait speed 0.89 m/s, 0.83 m/s, p = 0.043). Baseline hsCRP correlated with change in BATT (τb = 0.73, p = 0.04) and baseline DHEA-S correlated with change in gait speed (τb = 0.87, p = 0.02). This pilot study has assisted to refine the protocol for our larger study, which will further characterise these changes.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.