Evidence map›Paper›PMID 30642067›Full record

ArticleInternational journal of molecular sciences2019

Effect of Cyclic Stretch on Vascular Endothelial Cells and Abdominal Aortic Aneurysm (AAA): Role in the Inflammatory Response.

Martina Ramella, Giulia Bertozzi, Luca Fusaro, Maria Talmon, Marcello Manfredi, Marta Calvo Catoria, Francesco Casella, Carla Maria Porta, Renzo Boldorini, Luigia Grazia Fresu and 2 more

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 26 citations in OpenAlex.

  1. Vascular mechanical forces and vascular diseases.Journal of advanced research · 2026
    Review
  2. Review
  3. Article
  4. Article
  5. Review
  6. Role of Extracellular Matrix and Inflammation in Abdominal Aortic Aneurysm.International journal of molecular sciences · 2022
    Review
  7. Mechanosignals in abdominal aortic aneurysms.Frontiers in cardiovascular medicine · 2022
    Review
  8. Article
  9. Article
  10. Inflammation and Cardiovascular Diseases: The Most Recent Findings.International journal of molecular sciences · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Martina RamellaDepartment of Health Science, University of Piemonte Orientale (UPO), via Solaroli 17, 28100 Novara, Italy. martina.ramella@med.uniupo.it.
Giulia BertozziDepartment of Health Science, University of Piemonte Orientale (UPO), via Solaroli 17, 28100 Novara, Italy. gbertozzi.gb@gmail.com.
Luca FusaroDepartment of Health Science, University of Piemonte Orientale (UPO), via Solaroli 17, 28100 Novara, Italy. luca.fusaro@med.uniupo.it.
Maria TalmonDepartment of Health Science, University of Piemonte Orientale (UPO), via Solaroli 17, 28100 Novara, Italy. maria.talmon@med.uniupo.it.
Marcello ManfrediISALIT s.r.l., Spin-off of DISIT, University of Piemonte Orientale (UPO), 15121 Alessandria, Italy. marcello.manfredi@uniupo.it.
Marta Calvo CatoriaDepartment of Health Science, University of Piemonte Orientale (UPO), via Solaroli 17, 28100 Novara, Italy. marta.catoira@uniupo.it.
Francesco CasellaVascular Surgery Unit, Ospedale Maggiore della Carità, 28100 Novara, Italy. fcasella1973@gmail.com.
Carla Maria PortaVascular Surgery Unit, Ospedale Maggiore della Carità, 28100 Novara, Italy. carla.porta@maggioreosp.novara.it.
Renzo BoldoriniDepartment of Health Science, University of Piemonte Orientale (UPO), via Solaroli 17, 28100 Novara, Italy. renzo.boldorini@med.uniupo.it.
Luigia Grazia FresuDepartment of Health Science, University of Piemonte Orientale (UPO), via Solaroli 17, 28100 Novara, Italy. luigia.fresu@med.uniupo.it.
Emilio MarengoDepartment of Sciences and Technological Innovation, University of Piemonte Orientale (UPO), 15121 Alessandria, Italy. emilio.marengo@uniupo.it.
Francesca BoccafoschiDepartment of Health Science, University of Piemonte Orientale (UPO), via Solaroli 17, 28100 Novara, Italy. francesca.boccafoschi@med.uniupo.it.ORCID 0000-0002-6734-5447
Università degli Studi del Piemonte Orientale “Amedeo Avogadro” · ITFondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Abdominal aortic aneurysm (AAA) is a focal dilatation of the aorta, caused by both genetic and environmental factors. Although vascular endothelium plays a key role in AAA progression, the biological mechanisms underlying the mechanical stress involvement are only partially understood. In this study, we developed an

Indexed as

Aortic Aneurysm, AbdominalBioreactorsCell Culture TechniquesCell LineEndothelial CellsGene Regulatory NetworksHumansMatrix Metalloproteinase 9Models, BiologicalOxidative StressStress, MechanicalTumor Necrosis Factor-alphaMatrix Metalloproteinase 9MMP9 protein, humanTumor Necrosis Factor-alphaabdominal aortic aneurysmcalcificationcardiovascular diseasescyclic stretchinflammationoxidative stress

Identifiers

PMID30642067
PMCPMC6359538
OpenAlexW2910699422

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.