Evidence map›Paper›PMID 30642033›Full record

ArticleNutrients2019

Beneficial Effects of an Aged Black Garlic Extract in the Metabolic and Vascular Alterations Induced by a High Fat/Sucrose Diet in Male Rats.

Sara Amor, Daniel González-Hedström, Beatriz Martín-Carro, Antonio Manuel Inarejos-García, Paula Almodóvar, Marin Prodanov, Angel Luis García-Villalón, Miriam Granado

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 1 pooled it
9.3field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 1 synthesis or guideline pooled it, 54 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Review
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  14. Food & nutrition research · 2023
    Article
  15. Review
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  17. Article
  18. Article
  19. The Effect of Garlic (Clinical nutrition research · 2021
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Sara AmorDepartamento de Fisiología, Facultad de Medicina, Universidad Autónoma de Madrid. C/Arzobispo Morcillo n°2 28029 Madrid, Spain. sara.amor@uam.es.
Daniel González-HedströmDepartamento de Fisiología, Facultad de Medicina, Universidad Autónoma de Madrid. C/Arzobispo Morcillo n°2 28029 Madrid, Spain. dgonzalez@pharmactive.eu.
Beatriz Martín-CarroDepartamento de Fisiología, Facultad de Medicina, Universidad Autónoma de Madrid. C/Arzobispo Morcillo n°2 28029 Madrid, Spain. beatriz.martinc@uam.es.
Antonio Manuel Inarejos-GarcíaPharmactive Biotech Products SL, Parque Científico de Madrid, 28049 Madrid, Spain. aminarejos@pharmactive.eu.ORCID 0000-0002-4869-6188
Paula AlmodóvarPharmactive Biotech Products SL, Parque Científico de Madrid, 28049 Madrid, Spain. palmodovar@pharmactive.eu.
Marin ProdanovDepartamento de Química Física Aplicada, Facultad de Ciencias, CIAL (CEI, CSIC-UAM), Universidad Autónoma de Madrid, 28049 Madrid, Spain. marin.prodanov@uam.es.
Angel Luis García-VillalónDepartamento de Fisiología, Facultad de Medicina, Universidad Autónoma de Madrid. C/Arzobispo Morcillo n°2 28029 Madrid, Spain. angeluis.villalon@uam.es.
Miriam GranadoDepartamento de Fisiología, Facultad de Medicina, Universidad Autónoma de Madrid. C/Arzobispo Morcillo n°2 28029 Madrid, Spain. miriam.granado@uam.es.ORCID 0000-0001-9178-8822
Universidad Autónoma de Madrid · ESInstituto de Salud Carlos III · ES

Funding

Pharmactive Biotech Products 125300
6 · The paper itself

Abstract

Aged black garlic (ABG) is a functional food with antioxidant and anti-inflammatory properties. Recent studies also report its beneficial metabolic effects in a context of obesity or diabetes, although the mechanisms involved are poorly understood. The aim of this work was to analyze the effects of an ABG extract in the vascular and metabolic alterations induced by a high-fat/sucrose diet in rats. For this purpose, male Sprague⁻Dawley rats were fed either a standard chow (controls;

Indexed as

AdiponectinAdiposityAnimalsAntioxidantsBody WeightCholesterol, HDLDietary SucroseDiet, High-FatGarlicGene Expression RegulationGlucose Tolerance TestGlucose Transporter Type 4HypothalamusInsulinLeptinMaleAdiponectinAntioxidantsCholesterol, HDLDietary SucroseGlucose Transporter Type 4InsulinLeptinPlant ExtractsPPAR gammaReceptor, InsulinReceptors, Adrenergic, beta-3Slc2a4 protein, ratTriglyceridesUcp1 protein, ratUncoupling Protein 1adipose tissueaged black garliccardiovascularinsulinmetabolic syndromeobesityrat

Identifiers

PMID30642033
PMCPMC6356877
OpenAlexW2910688112

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.