Evidence map›Paper›PMID 30641957›Full record

ReviewInternational journal of molecular sciences2019

Platelet-Rich Plasma in Treatment of Temporomandibular Joint Dysfunctions: Narrative Review.

Francesca Zotti, Massimo Albanese, Luigi Fabrizio Rodella, Pier Francesco Nocini

Open access · goldAbstract readComparative StudyReview
In one paragraph

Review in International journal of molecular sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 1 pooled it
10.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 1 synthesis or guideline pooled it, 69 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Trial
  4. Article
  5. Review
  6. Prolotherapy for temporomandibular joint disorders: an updated comprehensive review.Journal of the Korean Association of Oral and Maxillofacial Surgeons · 2025
    Review
  7. Review
  8. Review
  9. Article
  10. Review
  11. Review
  12. Review
  13. Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Observational
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Francesca ZottiDepartment of Surgery, Dentistry, Paediatric and Gynaecology, University of Verona. Policlinico G. B. Rossi. Piazzale L. Scuro n.10, 37134 Verona, Italy. francesca.zotti@univr.it.ORCID 0000-0001-8325-2964
Massimo AlbaneseDepartment of Surgery, Dentistry, Paediatric and Gynaecology, University of Verona. Policlinico G. B. Rossi. Piazzale L. Scuro n.10, 37134 Verona, Italy. massimo.albanese@univr.it.ORCID 0000-0002-8108-0617
Luigi Fabrizio RodellaSection of Anatomy and Pathophysiology, Department of Clinical and Experimental Sciences, University of Brescia, 25100 Brescia, Italy. luigi.rodella@unibs.it.
Pier Francesco NociniDepartment of Surgery, Dentistry, Paediatric and Gynaecology, University of Verona. Policlinico G. B. Rossi. Piazzale L. Scuro n.10, 37134 Verona, Italy. pierfrancesco.nocini@univr.it.
University of Verona · ITUniversity of Brescia · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe aims of this narrative review were to examine up-to-date literature in order to evaluate the effectiveness of arthrocentesis or injections with platelet-rich plasma in temporomandibular affections and to compare them to arthrocentesis alone or with hyaluronic acid (HA) or to hyaluronic acid injections.

methodsThe search of international literature was made on the PMC, PubMed and Cochrane databases, including all full-length text of studies on humans focused on osteoarthritis and disc displacements and their treatment with platelet-rich plasma arthrocentesis or injections. All design studies were included in the review and they were examined for three different outcomes: pain, joint sound and mandibular motion. English papers were only selected.

resultsEven though the low number of studies in this field, arthrocentesis with platelet-rich plasma and platelet-rich plasma injections in temporomandibular disorders' management were found to be effective in reducing pain and joint sound as well as in improving mandibular motion in a maximum follow-up of 24 months.

conclusionComparison to arthrocentesis alone or to HA use in arthrocentesis or by injections provided encouraging results in terms of the effectiveness of platelet-rich plasma use.

Indexed as

ArthrocentesisHumansHyaluronic AcidInjectionsPain MeasurementPlatelet-Rich PlasmaRange of Motion, ArticularTemporomandibular Joint Dysfunction SyndromeTreatment OutcomeHyaluronic Acidarthrocentesishyaluronic acidinjectionplatelet-rich plasmatemporomandibular joint disorders (TMD)temporomandibular joint (TMJ)

Identifiers

PMID30641957
PMCPMC6358929
OpenAlexW2908930068

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.