Evidence map›Paper›PMID 30641909›Full record

ArticleMolecules (Basel, Switzerland)2019

Metabolomics Profiling Reveals Rehmanniae Radix Preparata Extract Protects against Glucocorticoid-Induced Osteoporosis Mainly via Intervening Steroid Hormone Biosynthesis.

Tianshuang Xia, Xin Dong, Yiping Jiang, Liuyue Lin, Zhimin Dong, Yi Shen, Hailiang Xin, Qiaoyan Zhang, Luping Qin

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 42 citations in OpenAlex.

  1. Review
  2. Article
  3. Multi-system Mechanisms in the Anti-osteoporotic Effects of Herbal Natural Products.Endocrine, metabolic & immune disorders drug targets · 2026
    Review
  4. Review
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  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
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  14. Article
  15. Article
  16. Article
  17. Article
  18. Miya Improves Osteoarthritis CharacteristicsFrontiers in pharmacology · 2022
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Tianshuang XiaDepartment of Pharmacognosy, Second Military Medical University School of Pharmacy, Shanghai 200433, China. xiatianshuang@smmu.edu.cn.
Xin DongDepartment of Pharmacognosy, Second Military Medical University School of Pharmacy, Shanghai 200433, China. dongxinsmmu@126.com.
Yiping JiangDepartment of Pharmacognosy, Second Military Medical University School of Pharmacy, Shanghai 200433, China. msjyp@163.com.
Liuyue LinDepartment of Pharmacognosy, Second Military Medical University School of Pharmacy, Shanghai 200433, China. linliuyue2016@163.com.
Zhimin DongDepartment of Pharmacognosy, Second Military Medical University School of Pharmacy, Shanghai 200433, China. dongzhiminedu@163.com.
Yi ShenDepartment of Pharmacognosy, Second Military Medical University School of Pharmacy, Shanghai 200433, China. 18065148122@163.com.
Hailiang XinDepartment of Pharmacognosy, Second Military Medical University School of Pharmacy, Shanghai 200433, China. hailiangxin@163.com.
Qiaoyan ZhangDepartment of Pharmacognosy, Second Military Medical University School of Pharmacy, Shanghai 200433, China. zqy1965@163.com.
Luping QinDepartment of Pharmacognosy, Second Military Medical University School of Pharmacy, Shanghai 200433, China. qinsmmu@126.com.
Second Military Medical University · CNZhejiang Chinese Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Rehmanniae Radix Preparata (RR), the dry rhizome of

Indexed as

MetabolomeMetabolomicsAnimalsBiomarkersBone and BonesCell DifferentiationCell ProliferationChromatography, High Pressure LiquidGlucocorticoidsHormonesMass SpectrometryOsteoblastsOsteoporosisPlant ExtractsRatsRehmanniaBiomarkersGlucocorticoidsHormonesPlant ExtractsSteroidsglucocorticoid-induced osteoporosismetabolomicsosteoblastRehmanniae Radix Preparatasteroid hormone biosynthesis

Identifiers

PMID30641909
PMCPMC6358733
OpenAlexW2910866266

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.