Evidence map›Paper›PMID 30641871›Full record

ArticleInternational journal of molecular sciences2019

Effects of Quercetin Metabolites on Triglyceride Metabolism of 3T3-L1 Preadipocytes and Mature Adipocytes.

Itziar Eseberri, Jonatan Miranda, Arrate Lasa, Andrea Mosqueda-Solís, Susana González-Manzano, Celestino Santos-Buelga, Maria P Portillo

Open access · goldAbstract readComparative Study
In one paragraph

Article in International journal of molecular sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
3.4field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it, 37 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Anti-Obesity Effects of Isorhamnetin and Isorhamnetin Conjugates.International journal of molecular sciences · 2022
    Review
  9. Review
  10. Nutraceutic Potential of Bioactive Compounds ofMolecules (Basel, Switzerland) · 2022
    Review
  11. Article
  12. Article
  13. A Micellar Formulation of Quercetin Prevents Cisplatin Nephrotoxicity.International journal of molecular sciences · 2021
    Article
  14. Article
  15. Review
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Itziar EseberriNutrition and Obesity Group, Department of Nutrition and Food Science, University of the Basque Country (UPV/EHU) and Lucio Lascaray Research Institute, 01006 Vitoria, Spain. itziar.eseberri@ehu.eus.ORCID 0000-0001-5036-963X
Jonatan MirandaNutrition and Obesity Group, Department of Nutrition and Food Science, University of the Basque Country (UPV/EHU) and Lucio Lascaray Research Institute, 01006 Vitoria, Spain. jonatan.miranda@ehu.eus.
Arrate LasaNutrition and Obesity Group, Department of Nutrition and Food Science, University of the Basque Country (UPV/EHU) and Lucio Lascaray Research Institute, 01006 Vitoria, Spain. arrate.lasa@ehu.eus.
Andrea Mosqueda-SolísNutrition and Obesity Group, Department of Nutrition and Food Science, University of the Basque Country (UPV/EHU) and Lucio Lascaray Research Institute, 01006 Vitoria, Spain. andreamosqueda.s@gmail.com.
Susana González-ManzanoGrupo de Investigación en Polifenoles (GIP-USAL), Facultad de Farmacia, Universidad de Salamanca, Campus Miguel de Unamuno s/n, 37007 Salamanca, Spain. susanagm@usal.es.
Celestino Santos-BuelgaGrupo de Investigación en Polifenoles (GIP-USAL), Facultad de Farmacia, Universidad de Salamanca, Campus Miguel de Unamuno s/n, 37007 Salamanca, Spain. csb@usal.es.ORCID 0000-0001-6592-5299
Maria P PortilloNutrition and Obesity Group, Department of Nutrition and Food Science, University of the Basque Country (UPV/EHU) and Lucio Lascaray Research Institute, 01006 Vitoria, Spain. mariapuy.portillo@ehu.eus.ORCID 0000-0003-0210-6549
University of the Basque Country · ESUniversidad de Salamanca · ES

Funding

Consejo Nacional de Ciencia y Tecnología Doctoral fellowship (Andrea Mosqueda-Solís)Euskal Herriko Unibertsitatea Doctoral fellowship (Itziar Eseberri)Eusko Jaurlaritza IT-572-13Instituto de Salud Carlos III CiberobnMinisterio de Economía y Competitividad AGL2015-64522-C2-2-R
6 · The paper itself

Abstract

Quercetin (Q) has rapid metabolism, which may make it worthwhile to focus on the potential activity of its metabolites. Our aim was to evaluate the triglyceride-lowering effects of Q metabolites in mature and pre-adipocytes, and to compare them to those induced by Q. 3T3-L1 mature and pre-adipocytes were treated with 0.1, 1 and 10 µM of Q, tamarixetin (TAM), isorhamnetin (ISO), quercetin-3-

Indexed as

3T3-L1 CellsAdipocytesAnimalsCell DifferentiationDisaccharidesDose-Response Relationship, DrugFatty Acids, NonesterifiedGene Expression ProfilingGene Expression RegulationGlycerolLipid MetabolismMiceQuercetinTriglycerides3-methylquercetinDisaccharidesFatty Acids, NonesterifiedGlycerolQuercetinquercetin 3-O-glucuronidequercetin 3'-sulfatetamarixetinTriglyceridesadipocytesmetabolitesQuercetintriglycerides

Identifiers

PMID30641871
PMCPMC6359054
OpenAlexW2909391408

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.