ArticleAmerican journal of respiratory and critical care medicine2019
Protein Phosphatase 2A Reduces Cigarette Smoke-induced Cathepsin S and Loss of Lung Function.
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Article in American journal of respiratory and critical care medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.
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35citing papers in PubMed
5.4field-weighted citation impact, top 4% of its field
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Who cites it
35 citing papers in PubMed, 54 citations in OpenAlex.
- The Emerging Role of the Cancerous Inhibitor of Protein Phosphatase 2A in Pulmonary Diseases.Medicina (Kaunas, Lithuania) · 2025Review
- Multiomics profiling reveals systemic biological responses to severe subacute exposure to heated tobacco products in rats.Scientific reports · 2025Article
- Metabolic reprogramming of macrophages in chronic obstructive pulmonary disease.Frontiers in immunology · 2025Review
- Advances on the Role of Lung Macrophages in the Pathogenesis of Chronic Obstructive Pulmonary Disease in the Era of Single-Cell Genomics.International journal of medical sciences · 2025Review
- Cathepsin S: molecular mechanisms in inflammatory and immunological processes.Frontiers in immunology · 2025Review
- Developmental immune network of airway lymphocytes and innate immune cells in patients with stable COPD.Frontiers in immunology · 2025Article
- Unveiling the Role of Cathepsins on Lung Function in Chronic Obstructive Pulmonary Disease: A Mendelian Randomization Analysis.International journal of chronic obstructive pulmonary disease · 2025Article
- The multifaceted roles of cathepsins in immune and inflammatory responses: implications for cancer therapy, autoimmune diseases, and infectious diseases.Biomarker research · 2024Review
- Neutrophil-Derived Proteases in Lung Inflammation: Old Players and New Prospects.International journal of molecular sciences · 2024Review
- Monocyte-derived alveolar macrophages are key drivers of smoke-induced lung inflammation and tissue remodeling.Frontiers in immunology · 2024Article
- Small-Molecule Activation of Protein Phosphatase 2A Counters Bleomycin-Induced Fibrosis in Mice.ACS pharmacology & translational science · 2023Article
- Evaluating Novel Protein Phosphatase 2A Activators as Therapeutics for Emphysema.American journal of respiratory cell and molecular biology · 2023Article
- Eosinophils promote pulmonary matrix destruction and emphysema via Cathepsin L.Signal transduction and targeted therapy · 2023Article
- Protein Phosphatase 2A as a Therapeutic Target in Pulmonary Diseases.Medicina (Kaunas, Lithuania) · 2023Review
- Using system biology and bioinformatics to identify the influences of COVID-19 co-infection with influenza virus on COPD.Functional & integrative genomics · 2023Article
- Senescence: Pathogenic Driver in Chronic Obstructive Pulmonary Disease.Medicina (Kaunas, Lithuania) · 2022Review
- Pre-Clinical Study Evaluating Novel Protein Phosphatase 2A Activators as Therapeutics for Neuroblastoma.Cancers · 2022Article
- Associative analysis of multi-omics data indicates that acetylation modification is widely involved in cigarette smoke-induced chronic obstructive pulmonary disease.Frontiers in medicine · 2022Article
- Circulating white blood cells and lung function impairment: the observational studies and Mendelian randomization analysis.Annals of medicine · 2021Observational
- Targeted Transcriptomic Analysis of C57BL/6 and BALB/c Mice During Progressive ChronicFrontiers in cellular and infection microbiology · 2021Article
Corrections and comments
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Authors and funding
14 authors at 5 institutions in 2 countries.
Declan F Doherty1 Airway Innate Immunity Research Group, Centre for Experimental Medicine, Wellcome-Wolfson Institute for Experimental Medicine, School of Medicine, Dentistry and Biomedical Sciences, Queen's University Belfast, Belfast, United Kingdom.
Sridesh Nath2 Division of Pulmonary and Critical Care Medicine, Department of Medicine, and.ORCID 0000-0001-7996-8820
Justin Poon2 Division of Pulmonary and Critical Care Medicine, Department of Medicine, and.ORCID 0000-0003-0411-4665
Robert F Foronjy2 Division of Pulmonary and Critical Care Medicine, Department of Medicine, and.ORCID 0000-0003-3964-5335
Michael Ohlmeyer4 Icahn School of Medicine at Mount Sinai, New York, New York.
Abdoulaye J Dabo2 Division of Pulmonary and Critical Care Medicine, Department of Medicine, and.ORCID 0000-0002-5127-1498
Matthias Salathe6 Department of Internal Medicine, University of Kansas Medical Center, Kansas City, Kansas.ORCID 0000-0001-9092-4861
Mark Birrell8 Respiratory Pharmacology Group, Airway Disease Section, National Heart and Lung Institute, Imperial College, London, United Kingdom; and.ORCID 0000-0001-6392-2086
Maria Belvisi8 Respiratory Pharmacology Group, Airway Disease Section, National Heart and Lung Institute, Imperial College, London, United Kingdom; and.ORCID 0000-0003-1652-4370
Nathalie Baumlin6 Department of Internal Medicine, University of Kansas Medical Center, Kansas City, Kansas.ORCID 0000-0002-5341-6785
Michael D Kim6 Department of Internal Medicine, University of Kansas Medical Center, Kansas City, Kansas.
Sinéad Weldon1 Airway Innate Immunity Research Group, Centre for Experimental Medicine, Wellcome-Wolfson Institute for Experimental Medicine, School of Medicine, Dentistry and Biomedical Sciences, Queen's University Belfast, Belfast, United Kingdom.ORCID 0000-0001-5628-6624
Clifford Taggart1 Airway Innate Immunity Research Group, Centre for Experimental Medicine, Wellcome-Wolfson Institute for Experimental Medicine, School of Medicine, Dentistry and Biomedical Sciences, Queen's University Belfast, Belfast, United Kingdom.ORCID 0000-0002-9930-2978
Patrick Geraghty2 Division of Pulmonary and Critical Care Medicine, Department of Medicine, and.ORCID 0000-0003-1647-5505
State University of New York · USQueen's University Belfast · GBUniversity of Miami · USAstraZeneca (United Kingdom) · GBPrinceton Satellite Systems (United States) · US
Funding
TRP-mediated airway inflammation by e-cigarette vapingR01HL139365 · NHLBI · UNIVERSITY OF KANSAS MEDICAL CENTER · PI SALATHE, MATTHIAS A · 2018 to 2021
$1.8MMedical Research Council MC_PC_13075Medical Research Council MR/P022847/1NHLBI NIH HHS R01 HL139365
Abstract
PubMed holds no abstract for this paper.
Indexed as
NicotianaAnimalsBronchiCase-Control StudiesCathepsinsCigarette SmokingDisease Models, AnimalEnzyme InhibitorsGene SilencingHumansLungMacrophages, AlveolarMiceMice, KnockoutOkadaic AcidProtein Phosphatase 2cathepsin SCathepsinsEnzyme InhibitorsOkadaic AcidProtein Phosphatase 2Smokecathepsin Schronic obstructive pulmonary diseasecigarette smokephosphatase
Identifiers
What OpenQuestion holds
Textmetadata
Read underepoch 390
Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.