Evidence map›Paper›PMID 30640765›Full record

ArticleDermatitis : contact, atopic, occupational, drug

Atopy and Sensitization to Allergens Known to Cause Systemic Contact Dermatitis.

Jeffrey F Scott, Rosalynn R Z Conic, InYoung Kim, Douglas Y Rowland, Susan T Nedorost

Abstract read
In one paragraph

Article in Dermatitis : contact, atopic, occupational, drug. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.9field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 11 citations in OpenAlex.

  1. Weak Sensitizers May Be Associated with CD80 Polymorphisms: Implications for Systemic Contact Dermatitis.JID innovations : skin science from molecules to population health · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Jeffrey F Scott
Rosalynn R Z Conic
InYoung Kim
Douglas Y RowlandDepartment of Population and Quantitative Health Sciences, Case Western Reserve University, Cleveland, OH.
Susan T Nedorost
University Hospitals of Cleveland · USCase Western Reserve University · US

Funding

TRAINING IN INVESTIGATIVE AND MOLECULAR DERMATOLOGYT32AR007569 · NIAMS · CASE WESTERN RESERVE UNIVERSITY · PI COOPER, KEVIN D · 1991 to 2019
$2.7M
NIAMS NIH HHS T32 AR007569
6 · The paper itself

Abstract

backgroundAtopic dermatitis (AD) associated with respiratory atopy may represent a form of systemic contact dermatitis (SCD), whereby AD flares after ingestion or inhalation of allergens.

objectiveThe aim of the study was to compare the prevalence of positive patch tests to allergens known to cause SCD in AD patients with and without respiratory atopy.

methodsThis is a retrospective study of patients with AD patch tested to 23 allergens known to cause SCD. Positive patch tests were compared between AD patients with and without respiratory atopy, stratified by age and wet or dry work occupation.

conclusionsChildren and adolescents, but not adults, with AD and respiratory atopy were more likely than age-matched AD patients without respiratory atopy to have positive patch tests to these allergens (odds ratio, 2.33; 95% confidence interval, 1.13-4.79). Moreover, AD patients with respiratory atopy and engaging in wet work, but not dry work, occupations were more likely than AD patients without respiratory atopy to have positive patch tests to allergens known to cause SCD (odds ratio, 1.47; 95% confidence interval, 1.05-2.06). Thus, respiratory atopy and wet work are associated with sensitization to allergens known to cause SCD in patients with AD, and patch testing may be valuable in identifying systemic triggers of dermatitis in these patients.

Indexed as

AdolescentAdultAllergensAsthmaDermatitis, Allergic ContactFemaleHumansHypersensitivity, ImmediateImmunizationMaleOccupational ExposureOdds RatioPatch TestsPrevalenceRespiratory HypersensitivityRetrospective StudiesAllergens

Identifiers

PMID30640765
PMCPMC6334658
OpenAlexW2910820282

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.