ArticleOphthalmic surgery, lasers & imaging retina2019
Culture-Proven Endophthalmitis After Intravitreal Injection: A 10-Year Analysis.
Article in Ophthalmic surgery, lasers & imaging retina, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
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The trial behind it
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Who cites it
8 citing papers in PubMed, 13 citations in OpenAlex.
- Delayed-onsetAmerican journal of ophthalmology case reports · 2025Article
- Morganella morganii and Enterococcus faecalis endophthalmitis following intravitreal injection.BMC ophthalmology · 2023Article
- Preventive factors, diagnosis, and management of injection-related endophthalmitis: a literature review.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2022Review
- Treatment Patterns and Outcomes in Bleb-Related Endophthalmitis: A 9-Year Analysis at a Tertiary Eye Center.Journal of vitreoretinal diseasesArticle
- Clinical Practice Update: Management of Infectious Endophthalmitis After Intravitreal Anti-VEGF Injection.Journal of vitreoretinal diseasesReview
- Outcomes of a Multicenter 10-Year Review of Postinjection Endophthalmitis and Associated Systemic Medical Comorbidities.Journal of vitreoretinal diseasesArticle
- Timing of vitrectomy for treatment of endophthalmitis after intravitreal anti-VEGF injection: a systematic literature review of case reports and series.Therapeutic advances in ophthalmologyReview
- Management Patterns and Outcomes for Intravitreal Injection-Related Endophthalmitis.Journal of vitreoretinal diseasesArticle
Corrections and comments
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Authors and funding
8 authors.
Funding
Abstract
BACKGROUND AND
objectiveTo report on the microbiology, management, and visual outcomes of intravitreal injection (IVI)-associated, culture-proven endophthalmitis. PATIENTS AND
methodsAll patients seen at a tertiary referral center with culture-proven endophthalmitis associated with an IVI between June 2007 and July 2017 were included in this retrospective analysis.
resultsThirty-five patients with culture-positive endophthalmitis following IVI were identified. All gram-positive organisms (34 of 35) were susceptible to vancomycin. Cases due to pathogens associated with oral or respiratory flora were common (31.4%, n = 11), presented earlier (2.0 days vs. 4.6 days, P < .001), were more likely to undergo pars plana vitrectomy (81.8% vs. 25.0%, P = .002) and had worse visual acuity outcomes.
conclusionIVI-associated endophthalmitis pathogens and anti-microbial susceptibilities in the Pacific Northwest are similar to those reported from other geographic locations. Bacteria associated with the oral and respiratory flora are common isolates that result in a more aggressive course and worse visual outcomes. [Ophthalmic Surg Lasers Imaging Retina. 2019;50:33-38.].
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.