Evidence map›Paper›PMID 30640271›Full record

ArticleJournal of pediatric gastroenterology and nutrition2019

Clinical Practice Approach to Nonalcoholic Fatty Liver Disease by Pediatric Gastroenterologists in the United States.

Warren L Shapiro, Elizabeth L Yu, Jennifer C Arin, Karen F Murray, Sabina Ali, Nirav K Desai, Stavra A Xanthakos, Henry C Lin, Naim Alkhouri, Reham Abdou and 20 more

Open access · greenAbstract read
In one paragraph

Article in Journal of pediatric gastroenterology and nutrition, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 26 citations in OpenAlex.

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  13. Perspectives on youth-onset nonalcoholic fatty liver disease.Endocrinology, diabetes & metabolism · 2020
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

30 authors at 18 institutions in 1 country.

Warren L ShapiroDivision of Gastroenterology, Hepatology, and Nutrition, Department of Pediatrics, University of California, San Diego School of Medicine, La Jolla.
Elizabeth L YuDivision of Gastroenterology, Hepatology, and Nutrition, Department of Pediatrics, University of California, San Diego School of Medicine, La Jolla.
Jennifer C ArinDivision of Gastroenterology, Hepatology, and Nutrition, Department of Pediatrics, University of California, San Diego School of Medicine, La Jolla.
Karen F MurrayDivision of Gastroenterology and Hepatology, Department of Pediatrics, University of Washington School of Medicine, and Seattle Children's Hospital, Seattle WA.
Sabina AliDepartment of Pediatric Gastroenterology, Stanford Children's Health, Stanford, CA.
Nirav K DesaiDivision of Gastroenterology, Hepatology and Nutrition, Boston Children's Hospital, Boston, MA.
Stavra A XanthakosCincinnati Children's Hospital Medical Center.
Henry C LinDivision of Gastroenterology, Hepatology, and Nutrition, Children's Hospital of Philadelphia, Philadelphia, PA.
Naim AlkhouriThe Texas Liver Institute.
Reham AbdouDigestive Diseases and Nutrition Center, Department of Pediatrics, Women and Children's Hospital of Buffalo, The State University of New York, Buffalo, NY.
Stephanie H AbramsTexas Children's Hospital.
Megan W ButlerPediatric Gastroenterology, Hepatology and Nutrition Duke University, Durham, NC.
Sarah A FaasseDepartment of Pediatric Gastroenterology, Hepatology, and Nutrition, Emory University School of Medicine.
Lynette A GillisDivision of Gastroenterology, Hepatology and Nutrition, Department of Pediatrics, Vanderbilt University School of Medicine, Nashville, TN.
Timothy A HadleyDepartment of Pediatric Gastroenterology, Hepatology, and Nutrition, Emory University School of Medicine.
Ajay K JainDepartment of Pediatrics, St. Louis University, St. Louis, MO.
Marianne KavanUniversity of Utah, Salt Lake City, UT.
Kattayoun KordyDepartment of Gastroenterology, Children's Hospital of Los Angeles, Los Angeles, CA.
Peter LeePediatric Specialists of Virginia Pediatric Gastroenterology and Hepatology, Ashburn, VA.
Jennifer PanganibanDivision of Gastroenterology, Hepatology and Nutrition, Children's Hospital of Philadelphia, PA.
John F PohlUniversity of Utah, Salt Lake City, UT.
Carol PotterGastroenterology, Hepatology and Nutrition, Nationwide Children's, Columbus, OH.
Bryan RudolphChildren's Hospital at Montefiore, Albert Einstein College of Medicine, Bronx, NY.
Shikha S SundaramSchool of Medicine, University of Colorado, Denver.
Shivali JoshiDivision of Gastroenterology, Hepatology, and Nutrition, Department of Pediatrics, University of California, San Diego School of Medicine, La Jolla.
James A ProudfootAltman Clinical and Translational Research Institute, University of California, San Diego School of Medicine, La Jolla, CA.
Nidhi P GoyalDivision of Gastroenterology, Hepatology, and Nutrition, Department of Pediatrics, University of California, San Diego School of Medicine, La Jolla.
Kathryn E HarlowDivision of Gastroenterology, Hepatology, and Nutrition, Department of Pediatrics, University of California, San Diego School of Medicine, La Jolla.
Kimberly P NewtonDivision of Gastroenterology, Hepatology, and Nutrition, Department of Pediatrics, University of California, San Diego School of Medicine, La Jolla.
Jeffrey B SchwimmerDivision of Gastroenterology, Hepatology, and Nutrition, Department of Pediatrics, University of California, San Diego School of Medicine, La Jolla.
University of California, San Diego · USRady Children's Hospital-San Diego · USUniversity of Washington · USBoston Children's Hospital · USChildren's Healthcare of Atlanta · USChildren's Hospital of Los Angeles · USChildren's Hospital of Philadelphia · USDuke University Hospital · USEmory University · USNationwide Children's Hospital · USSeattle Children's Hospital · USStanford Health Care · USThe University of Texas at San Antonio · USUniversity at Buffalo, State University of New York · USUniversity of California, Irvine · USUniversity of Colorado Denver · USVanderbilt University · USVirginia Cancer Specialists · US

Funding

UC San Diego Clinical and Translational Research InstituteUL1TR001442 · NCATS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI FIRESTEIN, GARY S, HOGARTH, MICHAEL · 2015 to 2024
$88.3M
San Diego Clinical and Translational Research InstituteUL1TR000100 · NCATS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI FIRESTEIN, GARY S · 2012 to 2015
$19.7M
Role of gut microbiota in total parenteral nutrition associated injuryR03DK121046 · NIDDK · SAINT LOUIS UNIVERSITY · PI JAIN, AJAY K. · 2019 to 2020
$227k
NCATS NIH HHS UL1 TR000100NCATS NIH HHS UL1 TR001442
6 · The paper itself

Abstract

objectivesNonalcoholic fatty liver disease (NAFLD) is common; however, no information is available on how pediatric gastroenterologists in the United States manage NAFLD. Therefore, study objectives were to understand how pediatric gastroenterologists in the US approach the management of NAFLD, and to identify barriers to care for children with NAFLD.

methodsWe performed structured one-on-one interviews to ascertain each individual pediatric gastroenterologist's approach to the management of NAFLD in children. Responses were recorded from open-ended questions regarding screening for comorbidities, recommendations regarding nutrition, physical activity, medications, and perceived barriers to care.

resultsResponse rate was 72.0% (486/675). Mean number of patients examined per week was 3 (standard deviation [SD] 3.5). Dietary intervention was recommended by 98.4% of pediatric gastroenterologists. Notably, 18 different dietary recommendations were reported. A majority of physicians provided targets for exercise frequency (72.6%, mean 5.6 days/wk, SD 1.6) and duration (69.9%, mean 40.2 minutes/session, SD 16.4). Medications were prescribed by 50.6%. Almost one-half of physicians (47.5%) screened for type 2 diabetes, dyslipidemia, and hypertension. Providers who spent more than 25 minutes at the initial visit were more likely to screen for comorbidities (P = 0.003). Barriers to care were reported by 92.8% with 29.0% reporting ≥3 barriers.

conclusionsThe majority of US pediatric gastroenterologists regularly encounter children with NAFLD. Varied recommendations regarding diet and exercise highlight the need for prospective clinical trials. NAFLD requires a multidimensional approach with adequate resources in the home, community, and clinical setting.

Indexed as

Non-alcoholic Fatty Liver DiseaseChildFemaleGastroenterologistsGastroenterologyHumansMalePediatricsPractice Patterns, Physicians'United States

Identifiers

PMID30640271
PMCPMC8053385
OpenAlexW2908775061

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.