Evidence map›Paper›PMID 30639980›Full record

ArticleJournal of the mechanical behavior of biomedical materials2019

Static and time-dependent mechanical response of organic matrix of bone.

Karanvir Saini, Dennis Discher, Navin Kumar

Open access · greenAbstract read
In one paragraph

Article in Journal of the mechanical behavior of biomedical materials, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.8field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Karanvir SainiChemical and Bio-molecular Engineering, University of Pennsylvania, Philadelphia, PA 19104, United States. Electronic address: karanvir@seas.upenn.edu.
Dennis DischerChemical and Bio-molecular Engineering, University of Pennsylvania, Philadelphia, PA 19104, United States.
Navin KumarDepartment of Mechanical Engineering, Indian Institute of Technology Ropar, Rupnagar, Punjab 140001, India.
University of Pennsylvania · USIndian Institute of Technology Ropar · IN

Funding

Building Enhanced Capability for the PennVet Multiphoton CoreS10OD021633 · OD · UNIVERSITY OF PENNSYLVANIA · PI FREEDMAN, BRUCE D · 2016 to 2016
$600k
NIH HHS S10 OD021633
6 · The paper itself

Abstract

Bone derives its mechanical strength from the complex arrangement of collagen fibrils (type-I primarily) reinforced with hydroxy-apatite (HAp) mineral crystals in extra- and intra-fibrillar compartments. This study demonstrates a novel approach to obtain organic matrix of bone through its demineralization as well as mechanically characterize it at small length scales using static and dynamic indentation techniques. Sample surface preparation protocol used in the present work maintained the surface integrity of demineralized bone samples which resulted sample surface of roughness (RMS) magnitude of approximately 14 nm (averaged over 1 × 1 μm

Indexed as

Bone and BonesMechanical PhenomenaAnimalsBiomechanical PhenomenaCattleMaterials TestingStress, MechanicalTime FactorsAFMBoneDemineralizationNanoindentationOrganic MatrixSEMSHG

Identifiers

PMID30639980
PMCPMC7971106
OpenAlexW2905647929

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.