Evidence map›Paper›PMID 30639794›Full record

ArticleDrug and alcohol dependence2019

PrEP awareness, eligibility, and interest among people who inject drugs in Baltimore, Maryland.

Susan G Sherman, Kristin E Schneider, Ju Nyeong Park, Sean T Allen, Derrick Hunt, C Patrick Chaulk, Brian W Weir

2 registry-linked trialsOpen access · greenAbstract read
In one paragraph

Article in Drug and alcohol dependence, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 75 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
75citing papers in PubMed, 2 pooled it
7.3field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05977881 nacompletednot on this mapstarted 2023, after this paper: background citation

Impact of a Novel HIV Peer Navigation and Overdose Prevention Intervention on Engagement in the HIV Prevention and Treatment Cascade

TypeinterventionalSponsorJohns Hopkins Bloomberg School of Public HealthRan2023 to 2026Enrolled493ConditionsHIV InfectionsArmsCHECKIT!
NCT07560046 phase4not yet recruitingnot on this mapstarted 2026, after this paper: background citation

Combating Related Epidemics in HCV Through Simplified Testing and Treatment. A Cluster Randomized Trial of Point-of-care Hepatitis C Testing and Treatment Among Key Populations

TypeinterventionalSponsorDuke UniversityRan2026 to 2030Enrolled1,280ConditionsHIV - Human Immunodeficiency Virus, Hepatitis B Virus (HBV), HEPATITIS C (HCV)ArmsCepheid GeneXpert HCV Test, Abbott Determine HIV - 1/2 Ag/Ab, Abbott Determine HbsAg 2, Sofosbuvir / Velpatasvir Oral Tablet [Epclusa]
3 · Its place in the literature

Who cites it

75 citing papers in PubMed, 2 syntheses or guidelines pooled it, 104 citations in OpenAlex.

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15 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Susan G ShermanDepartment of Health, Behavior and Society, Johns Hopkins Bloomberg School of Public Health, 624 N. Broadway, Baltimore, MD, 21205, USA. Electronic address: ssherman@jhsph.edu.
Kristin E SchneiderDepartment of Mental Health, Johns Hopkins Bloomberg School of Public Health, 624 N. Broadway, Baltimore, MD 21205, USA. Electronic address: kschne18@jhu.edu.
Ju Nyeong ParkDepartment of Epidemiology, Johns Hopkins Bloomberg School of Public Health, 624 N. Broadway, Baltimore, MD 21205, USA. Electronic address: ju.park@jhu.edu.
Sean T AllenDepartment of Health, Behavior and Society, Johns Hopkins Bloomberg School of Public Health, 624 N. Broadway, Baltimore, MD, 21205, USA. Electronic address: sallen63@jhu.edu.
Derrick HuntBaltimore City Health Department, 1001 East Fayette St, Baltimore, MD, 21202, USA. Electronic address: derrick.hunt@baltimorecity.gov.
C Patrick ChaulkBaltimore City Health Department, 1001 East Fayette St, Baltimore, MD, 21202, USA. Electronic address: patrick.chaulk@baltimorecity.gov.
Brian W WeirDepartment of Health, Behavior and Society, Johns Hopkins Bloomberg School of Public Health, 624 N. Broadway, Baltimore, MD, 21205, USA. Electronic address: bweir3@jhu.edu.
Johns Hopkins University · USBaltimore City Health Department · US

Funding

Vaccine Response and Immunotherapeutics SWGP30AI094189 · NIAID · JOHNS HOPKINS UNIVERSITY · PI Richard E. Chaisson · 2012 to 2026
$67.0M
NIDA Epidemiology Training Program: Johns Hopkins UniversityT32DA007292 · NIDA · JOHNS HOPKINS UNIVERSITY · PI RENEE M. JOHNSON, Brion S Maher · 1993 to 2026
$17.7M
NIAID NIH HHS P30 AI094189NIDA NIH HHS T32 DA007292
6 · The paper itself

Abstract

backgroundLimited research has examined pre-exposure prophylaxis (PrEP) interest among people who inject drugs (PWID). To date, few studies have examined the relationship between PrEP eligibility and PrEP interest among PWID.

methodsData were from an anonymous, cross-sectional survey of Baltimore Syringe Services Program (SSP) clients and non-client peers, restricted to HIV-uninfected participants (N = 265). Participants were classified as PrEP eligible/ineligible based on injection related criteria outlined in the CDC's PrEP guidelines. Participants were asked if they were previously aware of PrEP, would be interested in taking PrEP, and the ease of taking PrEP daily. Participants self-reported their sociodemographic characteristics, health diagnoses, and recent drug use, overdose, and drug treatment history. We estimated bivariate and multivariate logistic regression models to test for significant predictors of interest in PrEP.

resultsOne-quarter of PWID had previously heard of PrEP and 63% of the sample was interested in taking PrEP. Only two respondents were currently taking PrEP. The majority (89%) thought taking PrEP every day would be easy. In the presence of other variables, PrEP interest was associated with PrEP eligibility (adjusted odds ratio [aOR] = 2.46; 95% Confidence Interval [CI]:1.34,4.50) and the number of medical diagnoses (aOR = 1.16; 95% CI:1.01,1.33)

conclusionsMost PWID were unaware of PrEP but interested in taking it. PWID who were eligible for PrEP are more likely to be interested in taking it. Having co-morbid conditions was an important correlate of PrEP interest. These results underscore the importance of providers across the healthcare sector engaging PWID in discussions about PrEP.

Indexed as

AwarenessAdolescentAdultBaltimoreCross-Sectional StudiesFemaleHIV InfectionsHumansMaleMiddle AgedPre-Exposure ProphylaxisSubstance Abuse, IntravenousYoung AdultHIV preventioninjection drug usepre-exposure prophylaxis (PrEP)

Identifiers

PMID30639794
PMCPMC6436943
OpenAlexW2896926374

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.