Evidence map›Paper›PMID 30639696›Full record

ArticleGenomics, proteomics & bioinformatics2018

Integration of A Deep Learning Classifier with A Random Forest Approach for Predicting Malonylation Sites.

Zhen Chen, Ningning He, Yu Huang, Wen Tao Qin, Xuhan Liu, Lei Li

Abstract read
In one paragraph

Article in Genomics, proteomics & bioinformatics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Zhen ChenSchool of Basic Medicine, Qingdao University, Qingdao 266021, China.
Ningning HeSchool of Basic Medicine, Qingdao University, Qingdao 266021, China.
Yu HuangSchool of Data Science and Software Engineering, Qingdao University, Qingdao 266021, China.
Wen Tao QinDepartment of Biochemistry, Schulich School of Medicine and Dentistry, University of Western Ontario, London, Ontario N6A 5C1, Canada.
Xuhan LiuDepartment of Information Technology, Beijing Oriental Yamei Gene Technology Institute Co. Ltd., Beijing 100078, China. Electronic address: xuhanliu@amagene.cn.
Lei LiSchool of Basic Medicine, Qingdao University, Qingdao 266021, China; School of Data Science and Software Engineering, Qingdao University, Qingdao 266021, China; Qingdao Cancer Institute, Qingdao University, Qingdao 266021, China. Electronic address: leili@qdu.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

As a newly-identified protein post-translational modification, malonylation is involved in a variety of biological functions. Recognizing malonylation sites in substrates represents an initial but crucial step in elucidating the molecular mechanisms underlying protein malonylation. In this study, we constructed a deep learning (DL) network classifier based on long short-term memory (LSTM) with word embedding (LSTM

Indexed as

Deep LearningAmino AcidsAmino Acid SequenceAnimalsForecastingLysineMachine LearningMalonatesProtein Processing, Post-TranslationalAmino AcidsLysineMalonatesDeep learningLSTMMalonylationRandom forestRecurrent neural network

Identifiers

PMID30639696
PMCPMC6411950

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.