Evidence map›Paper›PMID 30639287›Full record

ArticleBiochimica et biophysica acta. Biomembranes2019

NMR analysis of free and lipid nanodisc anchored CEACAM1 membrane proximal peptides with Ca

Haike Ghazarian, Weidong Hu, Allen Mao, Tung Nguyen, Nagarajan Vaidehi, Stephen Sligar, John E Shively

Open access · greenAbstract read
In one paragraph

Article in Biochimica et biophysica acta. Biomembranes, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.4field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

  1. Mechanism and function of CEACAM1 splice isoforms.European journal of clinical investigation · 2024
    Review
  2. Structural aspects of CEACAM1 interactions.European journal of clinical investigation · 2024
    Review
  3. Solid-State NMR Study to Probe the Effects of Divalent Metal Ions (CaLangmuir : the ACS journal of surfaces and colloids · 2021
    Article
  4. Nanodiscs: A toolkit for membrane protein science.Protein science : a publication of the Protein Society · 2021
    Review
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Haike GhazarianDepartment of Molecular Imaging and Therapy, Diabetes, Metabolism and Research Institute of City of Hope, 1450 East Duarte Road, Duarte, CA 91010, United States of America; City of Hope Irell and Manella Graduate School of Biological Sciences, 1450 East Duarte road, Duarte, CA 91010, United States of America.
Weidong HuDepartment of Molecular Imaging and Therapy, Diabetes, Metabolism and Research Institute of City of Hope, 1450 East Duarte Road, Duarte, CA 91010, United States of America.
Allen MaoDepartment of Molecular Imaging and Therapy, Diabetes, Metabolism and Research Institute of City of Hope, 1450 East Duarte Road, Duarte, CA 91010, United States of America.
Tung NguyenDepartment of Molecular Imaging and Therapy, Diabetes, Metabolism and Research Institute of City of Hope, 1450 East Duarte Road, Duarte, CA 91010, United States of America.
Nagarajan VaidehiDepartment of Molecular Imaging and Therapy, Diabetes, Metabolism and Research Institute of City of Hope, 1450 East Duarte Road, Duarte, CA 91010, United States of America.
Stephen SligarDepartment of Biochemistry, University of Illinois, Urbana, IL 61801, United States of America.
John E ShivelyDepartment of Molecular Imaging and Therapy, Diabetes, Metabolism and Research Institute of City of Hope, 1450 East Duarte Road, Duarte, CA 91010, United States of America. Electronic address: jshively@coh.org.
City of Hope · USUniversity of Illinois Urbana-Champaign · US

Funding

Transgenic Mouse FacilityP30CA033572 · NCI · CITY OF HOPE/BECKMAN RESEARCH INSTITUTE · PI XIWEI WU · 1985 to 2026
$86.3M
Nanoscale Approaches to Understanding Membrane Protein FunctionR35GM118145 · NIGMS · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI STEPHEN G. SLIGAR · 2016 to 2026
$7.5M
Role of CEACAM1 in Epithelial Cell PolarizationR01CA084202 · NCI · CITY OF HOPE/BECKMAN RESEARCH INSTITUTE · PI SHIVELY, JOHN ERNEST · 2000 to 2010
$4.1M
NCI NIH HHS P30 CA033572NCI NIH HHS R01 CA084202NIGMS NIH HHS R35 GM118145
6 · The paper itself

Abstract

CEACAM1, a homotypic transmembrane receptor with 12 or 72 amino acid cytosolic domain isoforms, is converted from inactive cis-dimers to active trans-dimers by calcium-calmodulin (Ca

Indexed as

Models, MolecularAntigens, CDCalciumCalmodulinCell Adhesion MoleculesHumansNanostructuresNuclear Magnetic Resonance, BiomolecularPeptidesAntigens, CDCalciumCalmodulinCD66 antigensCell Adhesion MoleculesPeptidesCalmodulinCEACAM1Lipid nanodiscNMRPhosphorylation

Identifiers

PMID30639287
PMCPMC6524640
OpenAlexW2908844853

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.