ArticleArchives of physical medicine and rehabilitation2019
Nonlinguistic Cognitive Factors Predict Treatment-Induced Recovery in Chronic Poststroke Aphasia.
Article in Archives of physical medicine and rehabilitation, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01927302 (The Center for the Neurobiology of Language Recovery), which is not on this map. Cited by 46 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The Center for the Neurobiology of Language Recovery (CNLR)
Who cites it
46 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Comparative Efficacy of Cognitive Training for Post-Stroke Aphasia: A Systematic Review and Network Meta-Analysis.Neurorehabilitation and neural repair · 2024Pooled it
- Measurement of cross-language and cross-domain generalization following semantic feature-based anomia treatment in bilingual aphasia.Neuropsychological rehabilitation · 2026Trial
- Language Recovery after Brain Injury: A Structural Network Control Theory Study.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2022Trial
- Rapid Lexical Retrieval and Executive Functioning in Very Mild Aphasia.American journal of speech-language pathology · 2026Article
- The association between nonverbal fluency and anomia treatment outcomes in people with post-stroke aphasia.Frontiers in human neuroscience · 2026Article
- Network flexibility facilitates treatment-induced recovery in post-stroke aphasia.Brain communications · 2026Article
- Cognitive Functions Supporting Learning Over Time in Naming Treatment for Aphasia.Journal of speech, language, and hearing research : JSLHR · 2025Article
- Cross-language interaction during sequential anomia treatment in three languages: Evidence from a trilingual person with aphasia.Cortex; a journal devoted to the study of the nervous system and behavior · 2025Article
- Multifactorial interplay on language recovery following left-hemispheric stroke: A retrospective study.Journal of neuropsychology · 2025Article
- The curious case of the Cat Rescue: can picture narrative description inform visuospatial processing in aphasia?Frontiers in human neuroscience · 2025Article
- Treatment of aphasia in linguistically diverse populations: current and future directions.Frontiers in psychology · 2025Review
- Errorless and errorful learning in people with aphasia across novel-object pairing and word retrieval tasks.Aphasiology · 2024Article
- Evidence from aphasia suggests a bidirectional relationship between inner speech and executive function.Neuropsychologia · 2024Article
- Transcranial Direct Current Stimulation to Ameliorate Post-Stroke Cognitive Impairment.Brain sciences · 2024Review
- Disentangling neuroplasticity mechanisms in post-stroke language recovery.Brain and language · 2024Review
- Resting-state brain network connectivity is an independent predictor of responsiveness to language therapy in chronic post-stroke aphasia.Cortex; a journal devoted to the study of the nervous system and behavior · 2024Article
- Recursive Self-feedback Improved Speech Fluency in Two Patients with Chronic Nonfluent Aphasia.Aphasiology · 2024Article
- An electrophysiological and behavioral investigation of feedback-based learning in aphasia.Aphasiology · 2024Article
- Insights gained over 60 years on factors shaping post-stroke aphasia recovery: A commentary on Vignolo (1964).Cortex; a journal devoted to the study of the nervous system and behavior · 2024Article
- Unraveling the Thread of Aphasia Rehabilitation: A Translational Cognitive Perspective.Biomedicines · 2023Review
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
objectiveTo determine if pretreatment nonlinguistic cognition predicted language treatment outcomes and if so, which specific nonlinguistic cognitive subskills predicted naming therapy outcomes.
designRetrospective.
settingResearch clinic.
participantsStudy 1 included data from 67 persons with aphasia who underwent language treatment and a pretreatment cognitive-linguistic assessment battery (N=67). Study 2 included data from 27 study 1 participants who completed additional pretreatment nonlinguistic cognitive assessments.
interventions120-minute sessions of sentence comprehension (n=26) or naming treatment (n=41) 2 times per week for up to 10-12 weeks.
main outcome measuresProportion of potential maximal gain (PMG) (assessed immediately after treatment [10-12wk]; formula=mean posttreatment score-mean pretreatment score/total number of trained items-mean pretreatment score) and proportion of potential maximal gain maintained (PMGM) (assessed 12wk after posttreatment [22-24wk]; formula=mean maintenance score-mean pretreatment score/total number of trained items-mean pretreatment score) as outcome variables; and pretreatment assessment scores as predictor variables.
resultsIn study 1, 37% of participants demonstrated nonlinguistic cognitive deficits. Principal component analyses reduced assessment data to 2 components: linguistic and nonlinguistic cognition. Backward elimination regression revealed that higher linguistic and nonlinguistic cognitive function significantly predicted higher PMG after language therapy. In study 2, principal component analysis of only the nonlinguistic cognitive measures identified 3 components: executive function, verbal short-term memory, and visual short-term memory. Controlling for pretreatment apraxia of speech and auditory comprehension deficits, regression analyses revealed that higher executive function and visual short-term memory significantly predicted higher PMG and PMGM after naming therapy.
conclusionsPretreatment nonlinguistic cognitive function significantly influenced language treatment outcomes and maintenance of therapy gains.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.