ArticleAddictive behaviors2019
Mediation analysis with binary outcomes: Direct and indirect effects of pro-alcohol influences on alcohol use disorders.
Article in Addictive behaviors, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
20 citing papers in PubMed, 37 citations in OpenAlex.
- Evaluating Treatment Mechanisms of Varenicline: Mediation by Affect and Craving.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2022Trial
- Differential mechanisms of change in motivational interviewing versus health education for smoking cessation induction.Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors · 2021Trial
- Bullying victimization and depressive symptoms among left-behind children: a moderated mediation model involving Internet Addiction.Frontiers in psychiatry · 2026Article
- A systematic review of operational research modelling for alcohol consumption and its consequences.Health systems (Basingstoke, England) · 2026Review
- Mediating Role of Physical Activity on Associations Between Neighborhood Environments and Mental Health in China.Journal of urban health : bulletin of the New York Academy of Medicine · 2025Article
- Furloughed Employees' Voluntary Turnover: The Role of Procedural Justice, Job Insecurity, and Job Embeddedness.International journal of environmental research and public health · 2023Article
- Regression-Equivalent Effect Sizes for Latent Growth Modeling and Associated Null Hypothesis Significance Tests.Structural equation modeling : a multidisciplinary journal · 2023Article
- Afraid but misinformed: Conspiracist beliefs cancel the positive influence of fear of COVID-19 on vaccination intentions - Findings from a Romanian sample.Frontiers in psychology · 2023Article
- Cyber-Victimization Experience among Higher Education Students: Effects of Social Support, Loneliness, and Self-Efficacy.International journal of environmental research and public health · 2022Article
- Multidimensional Impulsive Personality Traits Mediate the Effect of Parent Substance Use Disorder on Adolescent Alcohol and Cannabis Use.Journal of youth and adolescence · 2022Article
- Are neighbourhood restaurants related to frequency of restaurant meals and dietary quality? Prevalence and changes over time in the Multi-Ethnic Study of Atherosclerosis.Public health nutrition · 2021Article
- Air Pollution Impairs Subjective Happiness by Damaging Their Health.International journal of environmental research and public health · 2021Article
- Parametric-Regression-Based Causal Mediation Analysis of Binary Outcomes and Binary Mediators: Moving Beyond the Rareness or Commonness of the Outcome.American journal of epidemiology · 2021Article
- Mediating Effect of Work Stress on the Associations Between Psychological Job Demands, Social Approval, and Workplace Violence Among Health Care Workers in Sichuan Province of China.Frontiers in public health · 2021Article
- Effect of Parameterization on Statistical Power and Effect Size Estimation in Latent Growth Modeling.Structural equation modeling : a multidisciplinary journal · 2021Article
- Neighborhood characteristics and transport walking: Exploring multiple pathways of influence using a structural equation modeling approach.Journal of transport geography · 2020Article
- Effect of antenatal depression on adverse birth outcomes in Gondar town, Ethiopia: A community-based cohort study.PloS one · 2020Article
- Improving the implementation of quantitative methods in addiction research: Introduction to the special issue.Addictive behaviors · 2019Article
- New Approaches for Estimation of Effect Sizes and their Confidence Intervals for Treatment Effects from Randomized Controlled Trials.The quantitative methods for psychology · 2019Article
- A Causal Approach to Functional Mediation Analysis with Application to a Smoking Cessation Intervention.Multivariate behavioral researchArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
Abstract
A risk factor or intervention (an independent variable) may influence a substance abuse outcome (the dependent variable) indirectly, by affecting an intervening variable (a mediator) that in turn affects that outcome. Mediation analysis is a statistical method commonly used to examine the interrelations among independent, mediating, and dependent variables to obtain the direct and indirect effects of an independent variable on a continuous dependent variable. However, mediation analysis may also be used with binary outcomes, such as a diagnosis of an alcohol use disorder (AUD). Study 1 demonstrated methods of mediation analysis with binary outcomes by examining the direct and indirect effects of pro-alcohol social influences on an AUD, as a function of: (a) the distribution of the independent variable (binary vs. continuous), (b) the frequency of the outcome (non-rare vs. rare), and (c) the effect metric (probability vs. odds ratio). Study 2 was a Monte Carlo (simulation) study of bias in the indirect effects based on estimates from the first study. These methods have wide applicability in addictions research because many key outcomes are binary, and mediation analysis is frequently used to study the causal mechanisms by which interventions and risk factors affect substance abuse.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.