Evidence map›Paper›PMID 30639113›Full record

ArticleCurrent biology : CB2019

All-or-None Context Dependence Delineates Limits of FEF Visual Target Selection.

Veronica E Scerra, M Gabriela Costello, Emilio Salinas, Terrence R Stanford

Abstract read
In one paragraph

Article in Current biology : CB, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Contributions of Distinct Attention Mechanisms to Saccadic Choices in a Gamified, Dynamic Environment.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Veronica E ScerraDepartment of Neurobiology and Anatomy, Wake Forest School of Medicine, 1 Medical Center Boulevard, Winston-Salem, NC 27157-1010, USA; Systems Neurobiology Laboratory, Salk Institute for Biological Studies, 10010 N. Torrey Pines Road, La Jolla, CA 92037, USA. Electronic address: vscerra@salk.edu.
M Gabriela CostelloDepartment of Neurobiology and Anatomy, Wake Forest School of Medicine, 1 Medical Center Boulevard, Winston-Salem, NC 27157-1010, USA; Laboratory of Sensorimotor Research, National Eye Institute, National Institutes of Health, Bethesda, MD 20892, USA.
Emilio SalinasDepartment of Neurobiology and Anatomy, Wake Forest School of Medicine, 1 Medical Center Boulevard, Winston-Salem, NC 27157-1010, USA.
Terrence R StanfordDepartment of Neurobiology and Anatomy, Wake Forest School of Medicine, 1 Medical Center Boulevard, Winston-Salem, NC 27157-1010, USA.

Funding

CRCNS: investigating perceptual processing speed and its impact on choice behaviorR01EY025172 · NEI · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI SALINAS, EMILIO, STANFORD, TERRENCE R · 2016 to 2024
$3.6M
Midbrain Mechanisms of Sensory-Guided Oculomotor ChoiceR01EY021228 · NEI · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI SALINAS, EMILIO, STANFORD, TERRENCE R · 2014 to 2017
$1.8M
Training Program in Multisensory ProcessesT32NS073553 · NINDS · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI STEIN, BARRY E · 2011 to 2020
$1.7M
CRCNS:Investigating perceptual processing speed and its impact on choice behaviorR01DA030750 · NIDA · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI SALINAS, EMILIO, STANFORD, TERRENCE R · 2010 to 2013
$1.2M
Frontal Mechanisms of Visuomotor ControlF31EY026494 · NEI · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI SCERRA, VERONICA EMILY · 2016 to 2017
$88k
Temporal correlates of saccadic choice accuracy in macaque FEF and OcThF31EY020107 · NEI · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI COSTELLO GRINBERG, MARIA GABRIELA · 2010 to 2011
$70k
NEI NIH HHS F31 EY020107NEI NIH HHS F31 EY026494NEI NIH HHS R01 EY021228NEI NIH HHS R01 EY025172NIDA NIH HHS R01 DA030750NINDS NIH HHS T32 NS073553
6 · The paper itself

Abstract

Choices of where to look are informed by perceptual judgments, which locate objects of current value or interest within the visual scene. This perceptual-motor transform is partly implemented in the frontal eye field (FEF), where visually responsive neurons appear to select behaviorally relevant visual targets and, subsequently, saccade-related neurons select the movements required to look at them. Here, we use urgent decision-making tasks to show (1) that FEF motor activity can direct accurate, visually informed choices in the complete absence of prior target-distracter discrimination by FEF visual responses and (2) that such discrimination by FEF visual cells shows an all-or-none reliance on the presence of stimulus attributes strongly associated with saliency-driven attentional allocation. The present findings suggest that FEF visual target selection is specific to visual judgments made on the basis of saliency and may not play a significant role in guiding saccadic choices informed solely by feature content.

Indexed as

Decision MakingAnimalsAttentionFrontal LobeMacaca mulattaMalePhotic StimulationVisual Perceptionattentiondecision makingeye movementsmotor planningoculomotorperceptionsaccadesaliencevisual search

Identifiers

PMID30639113
PMCPMC7105291

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.