Evidence map›Paper›PMID 30638828›Full record

ArticleSexual medicine2019

Erectile Dysfunction in 45-Year-Old Heterosexual German Men and Associated Lifestyle Risk Factors and Comorbidities: Results From the German Male Sex Study.

Jacqueline Hallanzy, Martina Kron, Veronika E Goethe, Frank-Michael Köhn, Maximilian Schmautz, Christian Arsov, Boris Hadaschik, Florian Imkamp, Jürgen E Gschwend, Kathleen Herkommer

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Sexual medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors.

Jacqueline HallanzyDepartment of Urology, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany.
Martina KronInstitute of Epidemiology and Medical Biometrics, University of Ulm, Ulm, Germany.
Veronika E GoetheDepartment of Urology, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany.
Frank-Michael KöhnAndrologicum Muenchen, European Academy of Andrology, Munich, Germany.
Maximilian SchmautzDepartment of Urology, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany.
Christian ArsovDepartment of Urology, University Hospital Dusseldorf, Heinrich Heine University, Dusseldorf, Germany.
Boris HadaschikDepartment of Urology, Heidelberg University Hospital, Ruprecht Karls University, Heidelberg, Germany; Department of Urology, Essen University Hospital, University Duisburg-Essen, Essen, Germany.
Florian ImkampClinic for Urology and Urologic Oncology, Hannover Medical School, Hannover, Germany.
Jürgen E GschwendDepartment of Urology, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany.
Kathleen HerkommerDepartment of Urology, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany. Electronic address: kathleen.herkommer@tum.de.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundErectile dysfunction (ED) is a common public health issue with a significant impact on quality of life. The associations between ED and several risk factors have been reported previously. The continuously increasing incidence of these factors is contributing to the increasing prevalence of ED.

aimTo assess ED prevalence and severity in a representative sample of 45-year-old German men and to analyze the association with risk factors (lifestyle risk factors/comorbidities).

methodsData were collected within the German Male Sex-Study. Randomly selected 45-year-old men were invited. A total of 10,135 Caucasian, heterosexual, sexually active men were included in this analysis. The self-reported prevalence of ED was assessed using the Erectile Function domain of the International Index of Erectile Function. Risk factors for ED were ascertained using self-report questionnaires. An anamnesis interview and a short physical examination were performed.

main outcome measureED prevalence and severity were evaluated in a cross-sectional design. The associations of ED with comorbidities (eg, depression, diabetes, hypertension, lower urinary tract symptoms) and lifestyle factors (ie, smoking, obesity, central obesity, physical inactivity, and poor self-perceived health-status) were analyzed by logistic regression.

resultsThe overall prevalence of ED was 25.2% (severe, 3.1%; moderate, 9.2%; mild to moderate, 4.2%; mild, 8.7%). Among the men with ED, 48.8% had moderate or severe symptoms. ED prevalence increased with the number of risk factors, to as high as 68.7% in men with 5-8 risk factors. In multiple logistic regression with backward elimination, the strongest associations with ED were found for depression (odds ratio [OR] = 1.87), poor self-perceived health status (OR = 1.72), lower urinary tract symptoms (OR = 1.68), and diabetes (OR = 1.38).

conclusionOne out of 4 men already had symptoms of ED at age 45. Almost one-half of the men with ED had moderate to severe symptoms. ED was strongly associated with each analyzed risk factor, and the prevalence and severity of ED increased with an increasing number of risk factors. Hallanzy J, Kron M, Goethe VE, et al. Erectile Dysfunction in 45-Year-Old Heterosexual German Men and Associated Lifestyle Risk Factors and Comorbidities: Results From the German Male Sex Study. Sex Med 2019;7:26-34.

Indexed as

Erectile DysfunctionGerman Male Sex-StudyMiddle-Aged MenPrevalenceRisk FactorsSeverity

Identifiers

PMID30638828
PMCPMC6377383

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.