Evidence map›Paper›PMID 30638266›Full record

ArticleClinical and experimental immunology2019

High concentrations of atorvastatin reduce in-vitro function of conventional T and regulatory T cells.

A L Rodríguez-Perea, M Rojas, P A Velilla-Hernández

Open access · greenAbstract read
In one paragraph

Article in Clinical and experimental immunology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 20 citations in OpenAlex.

  1. Statins as Repurposed Drugs in Gynecological Cancer: A Review.International journal of molecular sciences · 2022
    Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

A L Rodríguez-PereaGrupo Inmunovirología, Facultad de Medicina, Universidad de Antioquia UdeA, Medellín, Colombia.
M RojasGrupo de Inmunología Celular e Inmunogenética (GICIG), Facultad de Medicina, Instituto de Investigaciones Médicas, Universidad de Antioquia UdeA, Medellín, Colombia.
P A Velilla-HernándezGrupo Inmunovirología, Facultad de Medicina, Universidad de Antioquia UdeA, Medellín, Colombia.ORCID 0000-0003-0885-1320
Universidad de Antioquia · CO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Regulatory T cells (T

Indexed as

Antigens, CDAtorvastatinCells, CulturedCTLA-4 AntigenCytokinesFlow CytometryForkhead Transcription FactorsHumansInterleukin-2Leukocyte Common AntigensLeukocytes, MononuclearProgrammed Cell Death 1 ReceptorReceptors, CCR7T-Lymphocytes, RegulatoryTumor Necrosis Factor-alphaAntigens, CDAtorvastatinCTLA-4 AntigenCytokinesForkhead Transcription FactorsInterleukin-2Leukocyte Common AntigensProgrammed Cell Death 1 ReceptorReceptors, CCR7Tumor Necrosis Factor-alphaactivationCa2+ fluxFoxP3Regulatory T cellstatin

Identifiers

PMID30638266
PMCPMC6468172
OpenAlexW2909349682

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.