Evidence map›Paper›PMID 30638141›Full record

ReviewTissue engineering. Part B, Reviews2019

Beyond Cartilage Repair: The Role of the Osteochondral Unit in Joint Health and Disease.

Sarah I M Lepage, Naomi Robson, Hillary Gilmore, Ola Davis, Allyssa Hooper, Stephanie St John, Vashine Kamesan, Paul Gelis, Diana Carvajal, Mark Hurtig and 1 more

Abstract readReview
In one paragraph

Review in Tissue engineering. Part B, Reviews, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 57 papers.

0numbers the graph read from it
0cells of the map it votes in
57citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

57 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Review
  6. Review
  7. Three-dimensionally-printed biphasic PCL/Regenerative biomaterials · 2026
    Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Review
  14. Article
  15. Article
  16. Review
  17. Review
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Sarah I M Lepage1 Department of Biomedical Sciences, University of Guelph, Guelph, Canada.
Naomi Robson1 Department of Biomedical Sciences, University of Guelph, Guelph, Canada.
Hillary Gilmore1 Department of Biomedical Sciences, University of Guelph, Guelph, Canada.
Ola Davis1 Department of Biomedical Sciences, University of Guelph, Guelph, Canada.
Allyssa Hooper1 Department of Biomedical Sciences, University of Guelph, Guelph, Canada.
Stephanie St John1 Department of Biomedical Sciences, University of Guelph, Guelph, Canada.
Vashine Kamesan1 Department of Biomedical Sciences, University of Guelph, Guelph, Canada.
Paul Gelis1 Department of Biomedical Sciences, University of Guelph, Guelph, Canada.
Diana Carvajal1 Department of Biomedical Sciences, University of Guelph, Guelph, Canada.
Mark Hurtig2 Department of Clinical Studies, University of Guelph, Guelph, Canada.
Thomas G Koch1 Department of Biomedical Sciences, University of Guelph, Guelph, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

impact statementIn this comprehensive review, we are providing a holistic overview of osteochondral tissue development, disease, pain localization, as well as structural evaluation and current repair strategies. This review is intended to serve as a broad introduction to this multidisciplinary research area. It is a thorough examination of the biological aspects of the osteochondral unit from a tissue engineering perspective, highlighting the importance of the subchondral bone in chondral and osteochondral lesion repair and pain relief.

Indexed as

AnimalsBone and BonesCartilage, ArticularChondrocytesHumansKnee InjuriesTissue Engineeringbonecartilagecrosstalkosteochondral unittissue engineering

Identifiers

PMID30638141
PMCPMC6486663

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.