Evidence map›Paper›PMID 30637892›Full record

ArticleJournal of magnetic resonance imaging : JMRI2019

Rapid automated liver quantitative susceptibility mapping.

Ramin Jafari, Sujit Sheth, Pascal Spincemaille, Thanh D Nguyen, Martin R Prince, Yan Wen, Yihao Guo, Kofi Deh, Zhe Liu, Daniel Margolis and 3 more

Abstract read
In one paragraph

Article in Journal of magnetic resonance imaging : JMRI, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Observational
  7. Article
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  9. Article
  10. Toward a realistic in silico abdominal phantom for QSM.Magnetic resonance in medicine · 2023
    Article
  11. QSM Throughout the Body.Journal of magnetic resonance imaging : JMRI · 2023
    Review
  12. Article
  13. Quantitative susceptibility mapping (QSM) of the cardiovascular system: challenges and perspectives.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2022
    Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Ramin JafariMeinig School of Biomedical Engineering, Cornell University, Ithaca, New York, USA.
Sujit ShethDepartment of Pediatrics, Weill Medical College of Cornell University, New York, New York, USA.
Pascal SpincemailleDepartment of Radiology, Weill Medical College of Cornell University, New York, New York, USA.
Thanh D NguyenDepartment of Radiology, Weill Medical College of Cornell University, New York, New York, USA.
Martin R PrinceDepartment of Radiology, Weill Medical College of Cornell University, New York, New York, USA.ORCID 0000-0002-9883-0584
Yan WenMeinig School of Biomedical Engineering, Cornell University, Ithaca, New York, USA.
Yihao GuoDepartment of Radiology, Weill Medical College of Cornell University, New York, New York, USA.
Kofi DehDepartment of Radiology, Weill Medical College of Cornell University, New York, New York, USA.
Zhe LiuMeinig School of Biomedical Engineering, Cornell University, Ithaca, New York, USA.
Daniel MargolisDepartment of Radiology, Weill Medical College of Cornell University, New York, New York, USA.
Gary M BrittenhamDepartment of Pediatrics, Columbia University, New York, New York, USA.
Andrea S KieransDepartment of Radiology, Weill Medical College of Cornell University, New York, New York, USA.
Yi WangMeinig School of Biomedical Engineering, Cornell University, Ithaca, New York, USA.

Funding

QSM to Guide Iron Chelating Therapy in Transfusional Iron OverloadR01DK116126 · NIDDK · WEILL MEDICAL COLL OF CORNELL UNIV · PI BRITTENHAM, GARY M, SHETH, SUJIT · 2019 to 2023
$3.2M
Quantitative Mapping of Substantia Nigra Iron in Parkinson's DiseaseR01NS095562 · NINDS · WEILL MEDICAL COLL OF CORNELL UNIV · PI SHTILBANS, ALEXANDER, WANG, YI · 2016 to 2022
$3.1M
Multiple Sclerosis Lesion Magnetic Susceptibility ActivityR01NS090464 · NINDS · WEILL MEDICAL COLL OF CORNELL UNIV · PI WANG, YI · 2015 to 2020
$2.3M
Compact Representations of Dynamic Liver MRIR01CA181566 · NCI · WEILL MEDICAL COLL OF CORNELL UNIV · PI SPINCEMAILLE, PASCAL · 2015 to 2019
$1.9M
NCI NIH HHS R01 CA181566NIDDK NIH HHS R01 DK116126NINDS NIH HHS R01 NS090464NINDS NIH HHS R01 NS095562
6 · The paper itself

Abstract

backgroundAccurate measurement of the liver iron concentration (LIC) is needed to guide iron-chelating therapy for patients with transfusional iron overload. In this work, we investigate the feasibility of automated quantitative susceptibility mapping (QSM) to measure the LIC. PURPOSE: To develop a rapid, robust, and automated liver QSM for clinical practice. STUDY TYPE: Prospective. POPULATION: 13 healthy subjects and 22 patients. FIELD STRENGTH/SEQUENCES: 1.5 T and 3 T/3D multiecho gradient-recalled echo (GRE) sequence. ASSESSMENT: Data were acquired using a 3D GRE sequence with an out-of-phase echo spacing with respect to each other. All odd echoes that were in-phase (IP) were used to initialize the fat-water separation and field estimation (T STATISTICAL TESTS: IP and SPURS initialization methods in both healthy subjects and patients were compared using paired t-test and linear regression analysis to assess processing time and region of interest (ROI) measurements. Reproducibility of QSM, R

resultsLiver QSM using the IP method was found to be ~5.5 times faster than SPURS (P < 0.05) in initializing T DATA

conclusionUse of IP echo-based initialization enables robust water/fat separation and field estimation for automated, rapid, and reproducible liver QSM for clinical applications. LEVEL OF EVIDENCE: 1 Technical Efficacy: Stage 2 J. Magn. Reson. Imaging 2019;50:725-732.

Indexed as

Feasibility StudiesHumansImage Interpretation, Computer-AssistedImaging, Three-DimensionalIronIron OverloadLiverMagnetic Resonance ImagingProspective StudiesReproducibility of ResultsIronin-phase echoesliver iron overloadquantitative susceptibility mappingwater/fat separation

Identifiers

PMID30637892
PMCPMC6929208

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.