ArticleBrazilian journal of microbiology : [publication of the Brazilian Society for Microbiology]2019
Viral pathogens associated with acute lower respiratory tract infections in children younger than 5 years of age in Bulgaria.
Article in Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology], 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
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Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Prevalence of common respiratory viruses of infants with respiratory tract infections in European countries in the past decade: a systematic review and meta-analysis comparing between the pre-COVID-19, pandemic, and post-COVID-19 periods.European journal of pediatrics · 2026Pooled it
- Lung ultrasound versus chest X-ray in pediatric lower respiratory tract infections at a tertiary center: a prospective observational study.Italian journal of pediatrics · 2026Observational
- The prevalence and role of human respiratory syncytial virus in pediatric respiratory tract infections: a systematic review and meta-analysis of global data.EClinicalMedicine · 2026Article
- Prevalence and seasonality of viral pathogens associated with respiratory tract infections in children.Paediatrics & child health · 2025Article
- Clinical characteristics of acute lower respiratory tract infection caused by Omicron, respiratory syncytial virus, and influenza virus a in children in Chengdu: a retrospective study.Italian journal of pediatrics · 2025Article
- Pathogen Profile of Children Hospitalised with Viral Respiratory Infections in Galati County, Romania.Viruses · 2025Article
- Prevalence of respiratory viruses in children in Northeast Brazil: The scenario before the COVID-19 pandemic.IJID regions · 2025Article
- Article
- Rhinovirus infection and co-infection in children with severe acute respiratory infection during the COVID-19 pandemic period.Virulence · 2024Article
- Viral Acute Lower Respiratory Tract Infections (ALRI) in Rural Bangladeshi Children Prior to the COVID-19 Pandemic.Influenza and other respiratory viruses · 2024Article
- An item bank to measure health-related quality of life among young children (0-5-years-old) affected by respiratory illnesses - expert stakeholders and end-users from the Western Cape, South Africa.Health and quality of life outcomes · 2024Article
- Alterations in Patients' Clinical Outcomes and Respiratory Viral Pathogen Activity following the COVID-19 Pandemic.Viruses · 2023Observational
- An outbreak of RSV infections in a neonatology clinic during the RSV-season.BMC pediatrics · 2021Article
- Impact of Guidelines Publication on Acute Bronchiolitis Management: 10-Year Experience from a Tertiary Care Center in Italy.Microorganisms · 2021Article
- Prevalence and Risk Factors of Respiratory Syncytial Virus in Children under 5 Years of Age in the WHO European Region: A Systematic Review and Meta-Analysis.Journal of personalized medicine · 2021Article
- Prevalence and Genetic Characteristics of Human Bocaviruses Detected in Patients with Acute Respiratory Infections in Bulgaria.International journal of microbiology · 2021Article
- The Prevalence and Genetic Characterization of Human Metapneumovirus in Bulgaria, 2016-2019.Intervirology · 2021Article
- Peripheral blood T cells response in human parainfluenza virus-associated lower respiratory tract infection in children.Saudi journal of biological sciences · 2020Article
- Superior mesenteric vein thrombosis induced by influenza infection: A case report.World journal of clinical cases · 2020Article
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10 authors.
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Abstract
Acute lower respiratory infections (ALRIs) are a leading cause of morbidity and hospital admissions in children. This study aimed to determine the viral etiology of these infections in children aged < 5 years during three successive epidemic seasons in Bulgaria. Nasopharyngeal and throat specimens were collected from children with bronchiolitis and pneumonia during the 2015/2016, 2016/2017, and 2017/2018 seasons. The viral etiology was determined by individual real-time PCR assays against 11 respiratory viruses. Of the 515 children examined, 402 (78.1%) were positive for at least one virus. Co-infections with two and three viruses were found in 64 (15.9%) of the infected children. Respiratory syncytial virus (RSV) was the predominant pathogen (37.5%), followed by rhinoviruses (13.8%), metapneumovirus (9.1%), adenoviruses (7%), bocaviruses (7%), influenza A(H1N1)pdm09 (4.9%), A(H3N2) (4.3%), type B (4.1%), and parainfluenza viruses 1/2/3 (2.9%). RSV-B were more prevalent than RSV-A during the three seasons. At least one respiratory virus was identified in 82.6% and 70.1% of the children with bronchiolitis and pneumonia, respectively. Respiratory viruses, especially RSV, are principal pathogens of ALRIs in children aged < 5 years. Diagnostic testing for respiratory viruses using molecular methods may lead to the reduced use of antibiotics and may assist in measures to control infection.
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