Evidence map›Paper›PMID 30637602›Full record

ArticlePrevention science : the official journal of the Society for Prevention Research2019

Gay and Bisexual Men's Strategies to Maintain Daily Adherence to Their HIV Pre-exposure Prophylaxis (PrEP) Medication: Results from a Qualitative Study.

Christian Grov, Anthony W P Flynn, Alexa B D'Angelo, Javier Lopez-Rios, David W Pantalone, Ian W Holloway, Jeffrey T Parsons

Abstract read
In one paragraph

Article in Prevention science : the official journal of the Society for Prevention Research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
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  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Christian GrovDepartment of Community Health and Social Sciences, CUNY Graduate School of Public Health and Health Policy, 55 West 125th Street, New York, NY, 10027, USA. cgrov@sph.cuny.edu.
Anthony W P FlynnDepartment of Counseling Psychology, University of Wisconsin Madison, Madison, WI, USA.
Alexa B D'AngeloDepartment of Community Health and Social Sciences, CUNY Graduate School of Public Health and Health Policy, 55 West 125th Street, New York, NY, 10027, USA.
Javier Lopez-RiosDepartment of Community Health and Social Sciences, CUNY Graduate School of Public Health and Health Policy, 55 West 125th Street, New York, NY, 10027, USA.
David W PantaloneUniversity of Massachusetts Boston, Boston, MA, USA.
Ian W HollowayDepartment of Social Welfare, University of California Los Angeles, Los Angeles, CA, USA.
Jeffrey T ParsonsHunter College of CUNY, The Center for HIV/AIDS Educational Studies and Training (CHEST), The Graduate Center of CUNY, New York, NY, USA.

Funding

UCLA Rapid, Relevant, Rigorous Implementation Science HubP30MH058107 · NIMH · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI Nina Thawata Harawa · 1997 to 2026
$53.5M
Scientific and Technical CoreP2CHD041022 · NICHD · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI Martha Jane Bailey · 2016 to 2026
$6.9M
Club drug use and PrEP adherence in vulnerable menR21DA039019 · NIDA · GRADUATE SCHOOL OF PUBLIC HEALTH AND HEALTH POLICY · PI GROV, CHRISTIAN · 2015 to 2016
$430k
NICHD NIH HHS P2C HD041022NIDA NIH HHS R21 DA039019NIDA NIH HHS R21- DA039019NIMH NIH HHS P30 MH058107
6 · The paper itself

Abstract

Since FDA approval in 2012, HIV pre-exposure prophylaxis (PrEP) has been adopted by key populations, including gay and bisexual men (GBM), to reduce their HIV transmission risk. Given that PrEP is optimally effective when taken as prescribed, it is critical to understand the adherence strategies GBM use. We conducted one-on-one, semi-structured interviews with GBM taking PrEP in 2015-2016 (n = 103). Using thematic analysis, we identified six adherence strategies, with most participants (84.3%) utilizing multiple strategies to maintain adequate adherence: (1) integrating PrEP into part of a daily routine, (2) using a pillbox, (3) cognitive strategies/visual cues, (4) setting recurring smartphone alarms or reminders, (5) keeping medication on oneself at all times, and (6) partner or peer support for reminders and/or pill sharing. Overall, participants reported high PrEP adherence (M = 1.6 missed doses in the prior 30 days), though nearly all described missing at least one dose unintentionally in the past. Participants credited their high levels of adherence in part to the strategies they adopted. Providers working with GBM prescribed PrEP, especially patients reporting difficulties with adherence, might consider recommending any or all of the six strategies described in this study.

Indexed as

Pre-Exposure ProphylaxisTreatment Adherence and ComplianceAdultBisexualityHIV InfectionsHomosexuality, MaleHumansInterviews as TopicMaleQualitative ResearchSexual BehaviorYoung AdultAdherenceGay and bisexual menHIVPre-exposure prophylaxis (PrEP)Qualitative data

Identifiers

PMID30637602
PMCPMC6438208

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.