Evidence map›Paper›PMID 30637476›Full record

ArticleLung2019

The Effects of Aging on Exhaled Nitric Oxide (FeNO) in a North African Population.

Sonia Rouatbi, Ines Ghannouchi, Helmi Bensaad

Abstract readComparative Study
PubMed Publisher
In one paragraph

Article in Lung, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Correlation of FEThe clinical respiratory journal · 2025
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Sonia RouatbiDepartment of Physiology and Functional Explorations, Farhat HACHED Hospital, Sousse, Tunisia. sonia.rouatbi@gmail.com.ORCID 0000-0003-3411-1182
Ines GhannouchiDepartment of Physiology and Functional Explorations, Farhat HACHED Hospital, Sousse, Tunisia.
Helmi BensaadDepartment of Physiology and Functional Explorations, Farhat HACHED Hospital, Sousse, Tunisia.
Hôpital Farhat Hached · TN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo determine and explain the effect of age on exhaled nitric oxide values in North African healthy subjects aged from 5 to 83 years.

designProspective cross-sectional study.

methodsVolunteer children adults and elderly healthy subjects were included. A medical questionnaire was used to assess several subject characteristics. The levels of exhaled fraction of nitric oxide (FeNO) were measured by Medisoft HypAir FeNO method. Spirometry function test was done after the FeNO measurement. The following parameters were measured: forced vital capacity (FVC, L); 1st second forced expiratory volume (FEV

resultsA significant increase in FeNO is noted between groups with respective age ranges of (5, 17) and (17, 25) years with a breakpoint at 1,397,034 years. A significant decrease of FeNO is noted between groups with respective age ranges of (45, 55) and (55, 65) years with a breakpoint at 6,366,052 years. No statistical significant difference was found between females' and males' means FeNO data. Finally, SEL, obesity status, and hypertension contribute significantly in the variations of FeNO values.

conclusionThe development and aging of the lung touched non-respiratory functions and so modified FeNO values in healthy North African subjects.

Indexed as

ExhalationAdolescentAdolescent DevelopmentAdultAgedAged, 80 and overAge FactorsAgingBiomarkersBlack PeopleChildChild DevelopmentChild, PreschoolCross-Sectional StudiesFemaleForced Expiratory VolumeBiomarkersNitric OxideExhaled nitric oxideLung agingLung developmentNorth Africa

Identifiers

PMID30637476
OpenAlexW2910436802

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.