Evidence map›Paper›PMID 30637473›Full record

ArticleCancer immunology, immunotherapy : CII2019

STAT3 inhibition specifically in human monocytes and macrophages by CD163-targeted corosolic acid-containing liposomes.

Morten Nørgaard Andersen, Anders Etzerodt, Jonas H Graversen, Lisa C Holthof, Søren K Moestrup, Marianne Hokland, Holger J Møller

Open access · greenAbstract read
In one paragraph

Article in Cancer immunology, immunotherapy : CII, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 57 citations in OpenAlex.

  1. Therapeutic potential of targeting macrophage polarization in metastatic gastric cancer: a review on core mechanisms and clinical progress.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2026
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  8. Recent advances in drug delivery and targeting for the treatment of pancreatic cancer.Journal of controlled release : official journal of the Controlled Release Society · 2024
    Review
  9. Unraveling the complexity of STAT3 in cancer: molecular understanding and drug discovery.Journal of experimental & clinical cancer research : CR · 2024
    Review
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  16. Tumor-Associated Macrophage Subsets: Shaping Polarization and Targeting.International journal of molecular sciences · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Morten Nørgaard AndersenDepartment of Clinical Biochemistry, Aarhus University Hospital, Palle Juul-Jensen Boulevard 99, 8200, Aarhus N, Denmark. morten@biomed.au.dk.ORCID http://orcid.org/0000-0003-0820-7789
Anders EtzerodtDepartment of Biomedicine, Aarhus University, Aarhus, Denmark.
Jonas H GraversenDepartment of Molecular Medicine, University of Southern Denmark, Odense, Denmark.
Lisa C HolthofDepartment of Hematology, Amsterdam UMC, VU University Medical Center, Cancer Center Amsterdam, Amsterdam, The Netherlands.
Søren K MoestrupDepartment of Clinical Biochemistry, Aarhus University Hospital, Palle Juul-Jensen Boulevard 99, 8200, Aarhus N, Denmark.
Marianne HoklandDepartment of Biomedicine, Aarhus University, Aarhus, Denmark.
Holger J MøllerDepartment of Clinical Biochemistry, Aarhus University Hospital, Palle Juul-Jensen Boulevard 99, 8200, Aarhus N, Denmark.
Aarhus University · DKUniversity of Southern Denmark · DKAarhus University Hospital · DKCancer Center Amsterdam · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tumor-associated macrophages (TAMs) are of major importance in cancer-related immune suppression, and tumor infiltration by CD163

Indexed as

Antigens, CDAntigens, Differentiation, MyelomonocyticCD163 AntigenCells, CulturedCytokinesDrug CompoundingHumansInterleukin-10LiposomesMacrophagesMonocytesReceptors, Cell SurfaceSTAT3 Transcription FactorTriterpenesAntigens, CDAntigens, Differentiation, MyelomonocyticCD163 Antigencorosolic acidCytokinesInterleukin-10LiposomesReceptors, Cell SurfaceSTAT3 Transcription FactorTriterpenesCancerCD163Drug deliverySignal transducer and activator of transcription 3 (STAT3)Tumor-associated macrophage (TAM)

Identifiers

PMID30637473
PMCPMC11028169
OpenAlexW2909226523

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.