ArticleNeuroradiology2019
Atrophy of the ipsilateral mammillary body in unilateral hippocampal sclerosis shown by thin-slice-reconstructed volumetric analysis.
Article in Neuroradiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed, 10 citations in OpenAlex.
- MRI measures of hypothalamic injury are associated with glucagon-like peptide-1 receptor agonist treatment response in people with hypothalamic obesity.Diabetes, obesity & metabolism · 2021Trial
- Accelerated hippocampal atrophy in APOE ε4 homozygotes and females: Longitudinal findings from the Tohoku Medical Megabank MRI study.Neuroradiology · 2026Article
- Revisiting retrosplenial amnesia: Injury of the crus of the fornix following splenial hemorrhage - A 3D magnetic resonance imaging case report.Journal of clinical imaging science · 2026Article
- Do the mammillary bodies atrophy with aging? A magnetic resonance imaging study.Surgical and radiologic anatomy : SRA · 2023Article
- Interhemispheric asymmetrical change in gray matter volume in patients with unilateral hippocampal sclerosis.Journal of clinical imaging science · 2023Article
- Mammillary Body Atrophy in Temporal Lobe Epilepsy With Hippocampal Sclerosis.Journal of clinical neurology (Seoul, Korea) · 2022Article
- The Most Common Lesions Detected by Neuroimaging as Causes of Epilepsy.Medicina (Kaunas, Lithuania) · 2021Review
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Authors and funding
9 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeConventional volumetric analysis could not detect ipsilateral atrophy of the mammillary body in patients with unilateral hippocampal sclerosis. By using thin-slice-reconstructed volumetric analysis, we investigated whether the mammillary body volume is smaller on the hippocampal sclerosis side than in healthy subjects or the non-hippocampal sclerosis side.
methodsThis retrospective study included 45 patients with unilateral hippocampal sclerosis and 30 healthy subjects. Three-dimensional T1WI of 1 mm thicknesses were oversampled to a thickness of 0.2 mm (thin-slice-reconstructed images), and the mammillary bodies were segmented manually to determine mammillary body volume on each side. Mammillary body volumes on the hippocampal sclerosis side were compared with those in healthy subjects or the non-hippocampal sclerosis side.
resultsIn patients with right hippocampal sclerosis, right mammillary body volume was both significantly smaller than that in healthy subjects (30.3 ± 10.3 vs. 43.3 ± 8.07 mm
conclusionsIn this study, thin-slice-reconstructed volumetric analysis showed that, in patients with unilateral hippocampal sclerosis, mammillary body volume on the hippocampal sclerosis side is smaller than that in healthy subjects and the non-hippocampal sclerosis side.
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