Observational studyGraefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie2019
Relationship between the morphology of the foveal avascular zone and the degree of aniseikonia before and after vitrectomy in patients with unilateral epiretinal membrane.
Observational study in Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
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Who cites it
25 citing papers in PubMed, 34 citations in OpenAlex.
- Changes in Aniseikonia in Patients with Idiopathic Epiretinal Membrane Treated with Pars Plana Vitrectomy: A Meta-Analysis.Journal of clinical medicine · 2026Review
- OCTA Biomarkers Underlying Structure-Function Correlations in Idiopathic Epiretinal Membrane: A Systematic Review.Diagnostics (Basel, Switzerland) · 2025Review
- Impact of retinal traction induced by epiretinal membrane on aniseikonia.Scientific reports · 2024Article
- Association of Microvasculature Changes with Visual Outcomes in Idiopathic Epiretinal Membrane Surgery: A Clinical Trial.Journal of clinical medicine · 2024Article
- Relationship between long-term visual function and the ratio of foveal avascular zone area in eyes with macular hole and healthy fellow eyes.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2024Article
- Aniseikonia and retinal morphological changes in eyes undergoing macular hole surgery.Scientific reports · 2024Article
- Estimation of foveal avascular zone area from a B-scan OCT image using machine learning algorithms.PloS one · 2024Article
- Exploratory analysis of choriocapillaris vasculature as a biomarker of idiopathic epiretinal membrane.PloS one · 2024Observational
- Morphologic analysis of the foveal avascular zone for prediction of postoperative visual acuity in advanced idiopathic epiretinal membrane.Scientific reports · 2023Article
- Associations between macular retinal vasculature and severity of idiopathic epiretinal membrane.BMC ophthalmology · 2023Article
- Retinal Vascular Tortuosity Index Change after Idiopathic Epiretinal Membrane Surgery: Does Internal Limiting Membrane Peeling Affect Retinal Vascular Tortuosity?Diagnostics (Basel, Switzerland) · 2023Article
- Evaluating the relationship between induced aniseikonia and distance stereopsis.Annals of translational medicine · 2023Article
- Quantitative assessment of retinal microvascular remodeling in eyes that underwent idiopathic epiretinal membrane surgery.Frontiers in cell and developmental biology · 2023Article
- Long-Term Follow-Up of Macular Perfusion Evaluated by Optical Coherence Tomography Angiography after Rhegmatogenous Retinal Detachment Surgery.Journal of clinical medicine · 2022Article
- Preoperative ocular coherence tomographic prognosticators of visual acuity after idiopathic epiretinal membrane surgery.International ophthalmology · 2022Review
- Idiopathic Epiretinal Membrane: Microvasculature Analysis with Optical Coherence Tomography and Optical Coherence Tomography Angiography.Tomography (Ann Arbor, Mich.) · 2022Article
- Aniseikonia following intravitreal ranibizumab treatment for branch retinal vein occlusion.Japanese journal of ophthalmology · 2021Observational
- Influence of mild non-foveal involving epiretinal membrane on visual quality in eyes with multifocal intraocular lens implantation.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2021Article
- Evaluation of retinal vascular structure after epiretinal membrane surgery by optical coherence tomography angiography.International ophthalmology · 2021Article
- Association of foveal avascular zone with the metamorphopsia in epiretinal membrane.Scientific reports · 2020Article
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposePersistent metamorphopsia, particularly aniseikonia, is a troublesome problem which may occur after epiretinal membrane (ERM) surgery. To clarify if the preoperative foveal avascular zone (FAZ) morphology can be used as a predictor of postoperative residual aniseikonia, the morphological changes in the FAZ and the degree of aniseikonia between before and 12 months after vitrectomy for epiretinal membrane (ERM) were measured and analyzed.
methodsThirty patients, each with a unilateral idiopathic ERM, who underwent treatment between September 2016 and March 2017 were enrolled for this prospective case series study. Best-corrected visual acuity (BCVA), the degree of aniseikonia, central foveal thickness (CFT), FAZ area (FAZa), perimeter (FAZp), and circularity in ERM eyes were examined before and 1, 3, 6 and 12 months after surgery. The fellow eye without an ERM was also examined and used as the control. The interocular ratios of the CFT, FAZa, and FAZp in ERM eyes with those in control eyes were also calculated. Multiple regression analysis was performed on preoperative parameters that were found to be significantly correlated with the 12-month aniseikonia in univariate analyses.
resultsThe BCVA in the ERM eyes was significantly improved at 1 month after surgery (P < .0001) The degree of aniseikonia was significantly reduced only after 12 months (P = .004). The CFT had decreased significantly by 3 months after the surgery and continued decreasing thereafter (P < .0001). Both FAZa and FAZp were significantly smaller in the ERM eyes than in the control eyes throughout the study period (P < .0001 and P < .0001, respectively), with no change in either parameter over the study period. Correlation analyses revealed that the degree of aniseikonia was significantly correlated with pre- and postoperative CFT, CFT ratio, FAZa, FAZa ratio, FAZp, and FAZp ratio. Within preoperative OCT parameters, FAZa ratio remained significant after multiple regression analysis was performed (P < .0001).
conclusionsAniseikonia changed little over the long term following ERM surgery. Preoperative FAZ area ratio was identified as a significant predictor of postoperative aniseikonia.
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