Evidence map›Paper›PMID 30637413›Full record

ArticleIntegrative cancer biology & research2017

Intracellular Oxygen Concentration Determined By Mitochondrial Respiration Regulates Production of Reactive Oxygen Species.

Ara Kim Wiese, Sara Prior, Timothy C Chambers, Masahiro Higuchi

Open access · greenAbstract read
PubMed Full text at PMC
In one paragraph

Article in Integrative cancer biology & research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Ara Kim WieseDepartment of Biochemistry and Molecular Biology, University of Arkansas for Medical Sciences, USA.
Sara PriorDepartment of Biochemistry and Molecular Biology, University of Arkansas for Medical Sciences, USA.
Timothy C ChambersDepartment of Biochemistry and Molecular Biology, University of Arkansas for Medical Sciences, USA.
Masahiro HiguchiDepartment of Biochemistry and Molecular Biology, University of Arkansas for Medical Sciences, USA.
University of Arkansas for Medical Sciences · US

Funding

Prostate tumor progression by mutant mitochondrial DNAR01CA100846 · NCI · UNIV OF ARKANSAS FOR MED SCIS · PI CHAMBERS, TIMOTHY C. · 2003 to 2013
$2.1M
NCI NIH HHS R01 CA100846
6 · The paper itself

Abstract

Oxidative phosphorylation not only generates cellular energy via ATP synthesis, but also controls the intracellular oxygen level to minimize oxygen toxicity resulting from reactive oxygen species (ROS). These species include superoxide (O

Indexed as

Intracellular oxygenMitochondriaProstate cancerReactive oxygen species

Identifiers

PMID30637413
PMCPMC6326587
OpenAlexW3024241730

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.