Evidence map›Paper›PMID 30637351›Full record

ArticleNeurobiology of sleep and circadian rhythms2018

Rhythms of metabolism in adipose tissue and mitochondria.

Yasemin Onder, Carla B Green

Open access · goldAbstract read
In one paragraph

Article in Neurobiology of sleep and circadian rhythms, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.0field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 19 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Yasemin OnderDepartment of Neuroscience, University of Texas Southwestern Medical Center, Dallas, TX 75390-9111, USA.
Carla B GreenDepartment of Neuroscience, University of Texas Southwestern Medical Center, Dallas, TX 75390-9111, USA.
The University of Texas Southwestern Medical Center · US

Funding

Molecular mechanisms of mammalian circadian clock function - Renewal - 1R35GM127122 · NIGMS · UT SOUTHWESTERN MEDICAL CENTER · PI Carla B. Green · 2018 to 2026
$6.0M
Transcriptional Architecture and Chromatin Landscape of Circadian Clocks in AgingR01AG045795 · NIA · UT SOUTHWESTERN MEDICAL CENTER · PI GREEN, CARLA B., TAKAHASHI, JOSEPH S · 2013 to 2017
$1.5M
Circadian regulation of mitochondrial RNA polyadenylationR01GM111387 · NIGMS · UT SOUTHWESTERN MEDICAL CENTER · PI GREEN, CARLA B. · 2014 to 2017
$1.2M
Circadian dynamics of cytoplasmic mRNA polyadenylation and deadenylationR01GM112991 · NIGMS · UT SOUTHWESTERN MEDICAL CENTER · PI GREEN, CARLA B. · 2016 to 2018
$1.1M
NIA NIH HHS R01 AG045795NIGMS NIH HHS R01 GM111387NIGMS NIH HHS R01 GM112991NIGMS NIH HHS R35 GM127122
6 · The paper itself

Abstract

Circadian clocks synchronize the daily functions of organisms with environmental cues like light-dark cycles and feeding rhythms. The master clock in the suprachiasmatic nucleus in the hypothalamus of the brain and the many clocks in the periphery are organized in a hierarchical manner; the master clock synchronizes the peripheral clocks, and the peripheral clocks provide feedback to the master clock in return. Not surprisingly, it has been shown that circadian rhythms and metabolism are closely linked. Metabolic disorders like obesity have a large cost to the individual and society and they are marked by adipose tissue and mitochondrial dysfunction. Mitochondria are central to energy metabolism and have key functions in processes like ATP production, oxidative phosphorylation, reactive oxygen species production and Ca

Indexed as

Brown adiposeCircadianMitochondriaRhythmicThermogenesis

Identifiers

PMID30637351
PMCPMC6329595
OpenAlexW2789402135

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.