Evidence map›Paper›PMID 30637297›Full record

ArticleApplied in vitro toxicology2018

An

Iain A Perry, Keith J Sexton, Zoë C Prytherch, Jason L Blum, Judith T Zelikoff, Kelly A BéruBé

Abstract read
In one paragraph

Article in Applied in vitro toxicology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Iain A PerrySchool of Biosciences, Cardiff University, Museum Avenue, Cardiff, United Kingdom.
Keith J SextonSchool of Biosciences, Cardiff University, Museum Avenue, Cardiff, United Kingdom.
Zoë C PrytherchSchool of Biosciences, Cardiff University, Museum Avenue, Cardiff, United Kingdom.
Jason L BlumDepartment of Environmental Medicine, NYU School of Medicine, NYU Langone Medical Centre, Tuxedo, New York.
Judith T ZelikoffDepartment of Environmental Medicine, NYU School of Medicine, NYU Langone Medical Centre, Tuxedo, New York.
Kelly A BéruBéSchool of Biosciences, Cardiff University, Museum Avenue, Cardiff, United Kingdom.
Cardiff University · GBNYU Langone Health · US

Funding

RESEARCH IN ENVIRONMENTAL HEALTH SCIENCES (CENTER GRANT)P30ES000260 · NIEHS · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI COSTA, MAX · 1985 to 2020
$26.1M
NIEHS NIH HHS P30 ES000260
6 · The paper itself

Abstract

Approximately 1 million women smoke during pregnancy despite evidence demonstrating serious juvenile and/or adult diseases being linked to early-life exposure to cigarette smoke. Susceptibility could be determined by factors in previous generations, that is, prenatal or "maternal" exposures to toxins. Prenatal exposure to airborne pollutants such as mainstream cigarette smoke has been shown to induce early-life insults (i.e., gene changes) in Offspring that serve as biomarkers for disease later in life. In this investigation, we have evaluated genome-wide changes in the lungs of mouse Dams and their juvenile Offspring exposed prenatally to mainstream cigarette smoke. An additional lung model was tested alongside the murine model, as a means to find an alternative

Indexed as

in vitroin vivomainstream cigarette smokeprenatal exposuretoxicogenomics

Identifiers

PMID30637297
PMCPMC6326191
OpenAlexW2596577088

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.