Evidence map›Paper›PMID 30637223›Full record

ArticleJournal of clinical and translational hepatology2018

Healthy Donor Fecal Microbiota Transplantation for Recurrent Bacterial Cholangitis in Primary Sclerosing Cholangitis - A Single Case Report.

Cyriac Abby Philips, Philip Augustine, Nikhil Phadke

Registry-linked trialOpen access · diamondAbstract readCase Reports
In one paragraph

Article in Journal of clinical and translational hepatology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07509346 (Multicenter Clinical Trial to Evaluate the Efficacy and Safety of Fecal Microbiota Transplantation Versus Standard Treatment in Patients With Recurrent Non-Obstructive Acute Cholangitis - COLANBIOTA Trial), which is not on this map. Cited by 21 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 2 pooled it
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07509346 phase2not yet recruitingnot on this mapstarted 2026, after this paper: background citation

Multicenter Clinical Trial to Evaluate the Efficacy and Safety of Fecal Microbiota Transplantation Versus Standard Treatment in Patients With Recurrent Non-Obstructive Acute Cholangitis - COLANBIOTA Trial

TypeinterventionalSponsorPuerta de Hierro University HospitalRan2026 to 2029Enrolled44ConditionsCholangitis Acute, RecurrenceArmsFecal Microbial Transplantation
3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 2 syntheses or guidelines pooled it, 35 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Review
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  5. Article
  6. [Expert consensus on the clinical application of gut microbiota transplant therapy in chronic liver disease (version 2025)].Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology · 2025
    Article
  7. Review
  8. Review
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  10. Article
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  17. Modulating the Intestinal Microbiota: Therapeutic Opportunities in Liver Disease.Journal of clinical and translational hepatology · 2020
    Review
  18. Review
  19. The Efficacy of Washed Microbiota Transplantation onGastroenterology research and practice · 2020
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Cyriac Abby PhilipsThe Liver Unit, Cochin Gastroenterology Group, P.A.A., Ernakulam Medical Centre, National Highway Bypass (NH-66), Palarivattom, Kochi, Kerala, India.
Philip AugustineGastroenterology, Cochin Gastroenterology Group, P.A.A., Ernakulam Medical Centre, National Highway Bypass (NH-66), Palarivattom, Kochi, Kerala, India.
Nikhil PhadkeMolecular, Cellular and Developmental Biology, Genepath Dx, Phadke Hospital, Shivajinagar, Pune, Maharashtra, India.
GenePath Dx (India) · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recurrent acute bacterial cholangitis is a unique indication for liver transplantation in primary sclerosing cholangitis. We present the first report on utility of healthy donor fecal transplantation for management of recurrent acute bacterial cholangitis in a primary sclerosing cholangitis patient. We demonstrate the striking liver biochemistry, bile acid and bacterial community changes following intestinal microbiota transplantation associated with amelioration of recurrent cholangitis.

Indexed as

FMTGut microbiomeMicrobiotaSclerosing cholangitisStool transplant

Identifiers

PMID30637223
PMCPMC6328734
OpenAlexW2887447992

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.