SynthesisStroke and vascular neurology2018
Risk factors of haemorrhagic transformation for acute ischaemic stroke in Chinese patients receiving intravenous recombinant tissue plasminogen activator: a systematic review and meta-analysis.
Synthesis in Stroke and vascular neurology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
18 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Safety and efficacy of intravenous thrombolysis before mechanical thrombectomy in patients with atrial fibrillation.Systematic reviews · 2024Pooled it
- Risk factors of hemorrhagic transformation in acute ischaemic stroke: A systematic review and meta-analysis.Frontiers in neurology · 2023Pooled it
- Risk prediction models for intracranial hemorrhage in acute ischemic stroke patients receiving intravenous alteplase treatment: a systematic review.Frontiers in neurology · 2023Pooled it
- [Efficacy of intravenous thrombolysis for acute severe cerebral infarction and risk factors of poor prognosis: a randomized controlled trial in 152 cases].Nan fang yi ke da xue xue bao = Journal of Southern Medical University · 2021Trial
- Timosaponin B-II attenuates hemorrhagic transformation-driven acceleration of alzheimer disease-related pathology after ischemic stroke.Biochemistry and biophysics reports · 2026Article
- Association of FLAIR Positivity and Worse Outcomes After Intravenous Thrombolysis in Known-Onset Strokes: A Systematic Review and Meta-Analysis.Journal of clinical medicine · 2025Review
- Low Cerebral Blood Volume Index, Thrombectomy, and Prior Stroke Are Independently Associated With Hemorrhagic Transformation in Medium-Vessel Occlusion Ischemic Stroke.Stroke (Hoboken, N.J.) · 2024Article
- Development and validation of an explainable machine learning prediction model of hemorrhagic transformation after intravenous thrombolysis in stroke.Frontiers in neurology · 2024Article
- Predictors for Hemorrhagic Transformation among Patients with Ischemic Stroke Admitted in a Tertiary Hospital in the Philippines from July 2018-July 2019.Acta medica Philippina · 2024Article
- Prediction factors and clinical significance of different types of hemorrhagic transformation after intravenous thrombolysis.European journal of medical research · 2023Article
- Predictive accuracy of an ADC map for hemorrhagic transformation in acute ischemic stroke patients after successful recanalization with endovascular therapy.Annals of translational medicine · 2022Article
- Nomogram to predict hemorrhagic transformation for acute ischemic stroke in Western China: a retrospective analysis.BMC neurology · 2022Article
- Article
- A novel nomogram to predict hemorrhagic transformation in ischemic stroke patients after intravenous thrombolysis.Frontiers in neurology · 2022Article
- Association between malnutrition risk and hemorrhagic transformation in patients with acute ischemic stroke.Frontiers in nutrition · 2022Article
- Hemorrhagic Transformation After Ischemic Stroke: Mechanisms and Management.Frontiers in neurology · 2021Review
- Risk Factors and a Nomogram for Predicting Intracranial Hemorrhage in Stroke Patients Undergoing Thrombolysis.Neuropsychiatric disease and treatment · 2020Article
- Rt-PA thrombolytic therapy in patients with acute posterior circulation stroke: A retrospective study.Medicine internationalArticle
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective: To identify risk factors for haemorrhagic transformation in Chinese patients with acute ischaemic stroke treated with recombinant tissue plasminogen activator. Methods: We searched electronic databases including PubMed, EMBASE, CNKI and WanFang Data for studies reporting risk factors of haemorrhagic transformation after intravenous thrombolysis. Pooled OR, weighted mean difference (WMD) and 95% CI were estimated. Meta-analysis was performed by using Stata V.14.0 software. Results: A total of 14 studies were included. The results indicated that older age (WMD=3.46, 95% CI 2.26 to 4.66, I Conclusion: The current meta-analysis identified eight risk factors for post-thrombolysis haemorrhagic transformation in Chinese patients with acute ischaemic stroke. Given the risk of bias, these results should be explained with caution and do not justify withholding intravenous thrombolysis.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.