Evidence map›Paper›PMID 30637030›Full record

ArticlePharmacy practice

Evaluation of medication adherence among Lebanese diabetic patients.

Lara Mroueh, Dana Ayoub, Maya El-Hajj, Sanaa Awada, Samar Rachidi, Salam Zein, Amal Al-Hajje

Open access · diamondAbstract read
In one paragraph

Article in Pharmacy practice. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.6field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 26 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Lara MrouehClinical and Epidemiological Research Laboratory, Faculty of Pharmacy, Lebanese University. Beirut (Lebanon). laramroueh@outlook.com.ORCID 0000-0002-6747-4046
Dana AyoubClinical and Epidemiological Research Laboratory, Faculty of Pharmacy, Lebanese University. Beirut (Lebanon). danaayoub@hotmail.com.ORCID 0000-0001-9438-5324
Maya El-HajjClinical and Epidemiological Research Laboratory, Faculty of Pharmacy, Lebanese University. Beirut (Lebanon). hajj_maya@hotmail.com.ORCID 0000-0001-9747-5675
Sanaa AwadaClinical and Epidemiological Research Laboratory, Faculty of Pharmacy, Lebanese University. Beirut (Lebanon). sanaa3a@hotmail.com.ORCID 0000-0001-9482-2483
Samar RachidiClinical and Epidemiological Research Laboratory, Faculty of Pharmacy, Lebanese University. Beirut (Lebanon). samar.rachidi@outlook.com.ORCID 0000-0003-4781-9526
Salam ZeinClinical and Epidemiological Research Laboratory, Faculty of Pharmacy, Lebanese University. Beirut (Lebanon). salamzein@hotmail.com.ORCID 0000-0003-4401-7480
Amal Al-HajjeClinical and Epidemiological Research Laboratory, Faculty of Pharmacy, Lebanese University. Beirut (Lebanon). amalkeh@hotmail.com.ORCID 0000-0001-7810-3390
Lebanese University · LB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDiabetes type 2 is considered one of the main public health concerns. Lack of adherence to treatment leads to poor therapeutic outcome, poor glycemic control, and high risk for developing diabetes complications.

objectivesThe aim of this study is to evaluate adherence to oral antidiabetic medication in Diabetes type 2 Lebanese patients, and to evaluate factors leading to low adherence.

methodsA cross-sectional study was conducted in outpatients endocrinology clinics of two hospitals and four private clinics located in Beirut-Lebanon. Data was collected using a well-structured questionnaire by trained pharmacists. Adherence level was measured by the Lebanese Medication Adherence Scale (LMAS-14). Bivariate and multivariate analyses were conducted using SPSS version 20.

resultsOverall, 245 patients were included in the study with the majority being females (54.3%) and obese (47.8%). Only 29% of the participants had controlled glycemia (HbA1c <7%) with 31.8% of subjects had high adherence to their medication compared to 68.2% with low adherence. Increased working hours/day was associated with a decrease in adherence to oral antidiabetic medication (OR=0.31; 95% CI 0.11:0.88; p=0.029). Other factors significantly associated with decreased adherence to treatment were forgetfulness, high drug costs, complex treatment regimens, experiencing side effects, and perception of treatment inefficacy. Postponing physician office visits also decreased the probability of being adherent to oral antidiabetic medication (OR=0.36; 95% CI 0.15:0.86; p=0.022). Skipping or doubling the dose in case of hypo/hyperglycemia and the sensation of treatment burden also decreased medication adherence (OR=0.09; 95% CI 0.02:0.34; p=0.001, and OR=0.04; 95% CI 0.01:0.13; p<0.001 respectively).

conclusionsAdherence to oral antidiabetic medication is low for Lebanese patients, which leads to a poor glycemic control and increases the diabetes complications. Intervention programs including patient education strategies are essential to improve medication adherence.

Indexed as

Cross-Sectional StudiesDiabetes MellitusLebanonMedication AdherenceMultivariate AnalysisRisk FactorsTreatment Adherence and ComplianceType 2

Identifiers

PMID30637030
PMCPMC6322979
OpenAlexW2602696863

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.