ArticleIndian journal of anaesthesia2018
Endovascular treatment of acute ischaemic stroke under conscious sedation: Predictors of poor outcomes.
Article in Indian journal of anaesthesia, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed, 4 citations in OpenAlex.
- Acute cervical spinal disc prolapse masquerading as stroke, requiring emergency spinal surgery immediately following thrombolysis.Indian journal of anaesthesia · 2021Article
- The effect of anaesthetic exposure in presurgical period on delayed cerebral ischaemia and neurological outcome in patients with aneurysmal subarachnoid haemorrhage undergoing clipping of aneurysm: A retrospective analysis.Indian journal of anaesthesia · 2020Article
- Effect of Conscious Sedation vs. General Anesthesia on Outcomes in Patients Undergoing Mechanical Thrombectomy for Acute Ischemic Stroke: A Prospective Randomized Clinical Trial.Frontiers in neurology · 2020Article
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Authors and funding
4 authors at 2 institutions in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND AND
aimsThough, many practitioners prefer conscious sedation (CS), it is unclear which factors most influence neurological outcome following mechanical thrombectomy under CS. The aim of this retrospective study is to identify these factors.
methodsAfter institutional review board approval, data were collected for the patients >18 years of age who underwent endovascular treatment of AIS under CS at our comprehensive stroke centre between January 2009 and June 2015. The primary outcome measure was the modified Rankin Scale (mRS) at discharge. A good outcome was defined as mRS 0-3 and poor outcome as mRS 4-6. Univariate and logistic regression analysis were performed to identify the independent predictors of poor outcomes at discharge. A
resultsOne hundred two patients, aged 67 ± 16 years were included. The anterior cerebral circulation was affected in 88 patients (86%), and the median National Institute of Health Stroke Scale (NIHSS) score at presentation was 17.5 (range: 1-36). Overall, 21 (21%) patients had good outcome and 81 (79%) had poor outcome. Logistic regression identified the modified treatment in cerebral ischaemia (mTICI) score [odds ratio (OR): 0.443, confidence interval (CI): 0.244-0.805], NIHSS score (OR: 1.290, CI: 1.125-1.481) and previous transient ischaemic attack (TIA) (OR: 6.988, CI: 1.342-36.380) as significant independent predictors of poor outcome at discharge.
conclusionThe outcome of patients who underwent endovascular treatment of AIS under CS depends on the mTICI score, NIHSS score and history of previous TIA.
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