Evidence map›Paper›PMID 30636564›Full record

ArticleThe Journal of neuropsychiatry and clinical neurosciences2019

Brain MR Radiomics to Differentiate Cognitive Disorders.

Sara Ranjbar, Stefanie N Velgos, Amylou C Dueck, Yonas E Geda, J Ross Mitchell, Alzheimer's Disease Neuroimaging Initiative

Abstract read
In one paragraph

Article in The Journal of neuropsychiatry and clinical neurosciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  14. Radiomics approach in the neurodegenerative brain.Aging clinical and experimental research · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Sara RanjbarThe Department of Research, Mayo Clinic Arizona, Phoenix (Ranjbar); the Center for Clinical and Translational Science, Mayo Clinic Graduate School of Biomedical Sciences (Velgos); the Department of Biostatistics, Mayo Clinic Arizona, Phoenix (Dueck); the Department of Psychiatry and Psychology, Mayo Clinic Arizona, Phoenix (Geda); the Department of Neurology, Mayo Clinic Arizona, Phoenix (Geda), and the Department of Physiology and Biomedical Engineering, Mayo Clinic Arizona, Phoenix (Mitchell).
Stefanie N VelgosThe Department of Research, Mayo Clinic Arizona, Phoenix (Ranjbar); the Center for Clinical and Translational Science, Mayo Clinic Graduate School of Biomedical Sciences (Velgos); the Department of Biostatistics, Mayo Clinic Arizona, Phoenix (Dueck); the Department of Psychiatry and Psychology, Mayo Clinic Arizona, Phoenix (Geda); the Department of Neurology, Mayo Clinic Arizona, Phoenix (Geda), and the Department of Physiology and Biomedical Engineering, Mayo Clinic Arizona, Phoenix (Mitchell).
Amylou C DueckThe Department of Research, Mayo Clinic Arizona, Phoenix (Ranjbar); the Center for Clinical and Translational Science, Mayo Clinic Graduate School of Biomedical Sciences (Velgos); the Department of Biostatistics, Mayo Clinic Arizona, Phoenix (Dueck); the Department of Psychiatry and Psychology, Mayo Clinic Arizona, Phoenix (Geda); the Department of Neurology, Mayo Clinic Arizona, Phoenix (Geda), and the Department of Physiology and Biomedical Engineering, Mayo Clinic Arizona, Phoenix (Mitchell).
Yonas E GedaThe Department of Research, Mayo Clinic Arizona, Phoenix (Ranjbar); the Center for Clinical and Translational Science, Mayo Clinic Graduate School of Biomedical Sciences (Velgos); the Department of Biostatistics, Mayo Clinic Arizona, Phoenix (Dueck); the Department of Psychiatry and Psychology, Mayo Clinic Arizona, Phoenix (Geda); the Department of Neurology, Mayo Clinic Arizona, Phoenix (Geda), and the Department of Physiology and Biomedical Engineering, Mayo Clinic Arizona, Phoenix (Mitchell).
J Ross MitchellThe Department of Research, Mayo Clinic Arizona, Phoenix (Ranjbar); the Center for Clinical and Translational Science, Mayo Clinic Graduate School of Biomedical Sciences (Velgos); the Department of Biostatistics, Mayo Clinic Arizona, Phoenix (Dueck); the Department of Psychiatry and Psychology, Mayo Clinic Arizona, Phoenix (Geda); the Department of Neurology, Mayo Clinic Arizona, Phoenix (Geda), and the Department of Physiology and Biomedical Engineering, Mayo Clinic Arizona, Phoenix (Mitchell).
Alzheimer's Disease Neuroimaging InitiativeThe Department of Research, Mayo Clinic Arizona, Phoenix (Ranjbar); the Center for Clinical and Translational Science, Mayo Clinic Graduate School of Biomedical Sciences (Velgos); the Department of Biostatistics, Mayo Clinic Arizona, Phoenix (Dueck); the Department of Psychiatry and Psychology, Mayo Clinic Arizona, Phoenix (Geda); the Department of Neurology, Mayo Clinic Arizona, Phoenix (Geda), and the Department of Physiology and Biomedical Engineering, Mayo Clinic Arizona, Phoenix (Mitchell).

Funding

Alzheimer's Disease Neuroimaging Initiative - SupplementU01AG024904 · NIA · NORTHERN CALIFORNIA INSTITUTE RES &EDUC · PI WEINER, MICHAEL W · 2004 to 2015
$121.0M
Mayo Clinic Center for Translational Science ActivitiesUL1TR000135 · NCATS · MAYO CLINIC ROCHESTER · PI KHOSLA, SUNDEEP · 2012 to 2015
$41.2M
NCATS NIH HHS UL1 TR000135NIA NIH HHS U01 AG024904
6 · The paper itself

Abstract

objectiveSubtle and gradual changes occur in the brain years before cognitive impairment due to age-related neurodegenerative disorders. The authors examined the utility of hippocampal texture analysis and volumetric features extracted from brain magnetic resonance (MR) data to differentiate between three cognitive groups (cognitively normal individuals, individuals with mild cognitive impairment, and individuals with Alzheimer's disease) and neuropsychological scores on the Clinical Dementia Rating (CDR) scale.

methodsData from 173 unique patients with 3-T T

resultsThe results show promise for hippocampal texture analysis to distinguish between no impairment and early stages of impairment. Volumetric features were more successful at differentiating between no impairment and advanced stages of impairment.

conclusionsMR radiomics may be a promising tool to classify various cognitive groups.

Indexed as

AgedAlzheimer DiseaseAtrophyCognitive DysfunctionDatabases, FactualFemaleHippocampusHumansImage Processing, Computer-AssistedMachine LearningMagnetic Resonance ImagingMaleMental Status and Dementia TestsAlzheimer’s DiseaseCognitive DisordersDementiaImaging TechniquesNeuropsychiatric Rating Scales

Identifiers

PMID30636564
PMCPMC6626704

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.