Evidence map›Paper›PMID 30636525›Full record

SynthesisJournal of the American Heart Association2019

Radial Artery Versus Right Internal Thoracic Artery Versus Saphenous Vein as the Second Conduit for Coronary Artery Bypass Surgery: A Network Meta-Analysis of Clinical Outcomes.

Mario Gaudino, Roberto Lorusso, Mohamed Rahouma, Ahmed Abouarab, Derrick Y Tam, Cristiano Spadaccio, Gaëlle Saint-Hilary, Jeremy Leonard, Mario Iannaccone, Fabrizio D'Ascenzo and 9 more

Open access · goldAbstract readSystematic ReviewNetwork Meta-Analysis
In one paragraph

Synthesis in Journal of the American Heart Association, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 2 pooled it
13.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 2 syntheses or guidelines pooled it, 102 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Anterolateral territory coronary artery bypass grafting strategies: a non-inferiority randomized clinical trial: the AMI-PONT trial.European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery · 2023
    Trial
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  15. Survival of multiple arterial grafting in diabetic populations: a 20-year national experience.European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery · 2023
    Article
  16. Article
  17. Review
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  19. Adipocyte-derived relaxing factor-a fat load to be learnt.European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery · 2022
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 11 institutions in 5 countries.

Mario Gaudino1 Department of Cardio-Thoracic Surgery Weill Cornell Medicine New York NY.
Roberto Lorusso2 Department of Cardio-Thoracic Surgery Heart & Vascular Centre Maastricht University Medical Hospital and CARIM (Cardiovascular Research Institute Maastricht) Maastricht The Netherlands.
Mohamed Rahouma1 Department of Cardio-Thoracic Surgery Weill Cornell Medicine New York NY.
Ahmed Abouarab1 Department of Cardio-Thoracic Surgery Weill Cornell Medicine New York NY.
Derrick Y Tam3 Schulich Heart Centre Sunnybrook Health Science University of Toronto Canada.
Cristiano Spadaccio4 Department of Cardiothoracic Surgery Golden Jubilee National Hospital Glasgow United Kingdom.
Gaëlle Saint-Hilary6 Department of Matematical Sciences Politecnico di Torino Turin Italy.
Jeremy Leonard1 Department of Cardio-Thoracic Surgery Weill Cornell Medicine New York NY.
Mario Iannaccone7 Department of Cardiology "Città della Scienza e della Salute" University of Turin Italy.
Fabrizio D'Ascenzo7 Department of Cardiology "Città della Scienza e della Salute" University of Turin Italy.
Antonino Di Franco1 Department of Cardio-Thoracic Surgery Weill Cornell Medicine New York NY.
Giovanni Soletti1 Department of Cardio-Thoracic Surgery Weill Cornell Medicine New York NY.
Mohamed K Kamel1 Department of Cardio-Thoracic Surgery Weill Cornell Medicine New York NY.
Christopher Lau1 Department of Cardio-Thoracic Surgery Weill Cornell Medicine New York NY.
Leonard N Girardi1 Department of Cardio-Thoracic Surgery Weill Cornell Medicine New York NY.
Thomas A Schwann8 University of Toledo Medical Center Toledo OH.
Umberto Benedetto9 School of Clinical Sciences Bristol Heart Institute University of Bristol United Kingdom.
David P Taggart10 University of Oxford United Kingdom.
Stephen E Fremes3 Schulich Heart Centre Sunnybrook Health Science University of Toronto Canada.
Cornell University · USWeill Cornell Medicine · USUniversity of Turin · ITMaastricht University Medical Centre · NLNIHR Bristol Cardiovascular Biomedical Research Unit · GBPolytechnic University of Turin · ITSunnybrook Health Science Centre · CAUniversity of Glasgow · GBUniversity of Oxford · GBUniversity of Toledo Medical Center · USUniversity of Toronto · CA

Funding

British Heart Foundation PG/11/19/28827British Heart Foundation PG/13/9/29990Medical Research Council MR/J015350/1
6 · The paper itself

Abstract

Background There remains uncertainty regarding the second-best conduit after the internal thoracic artery in coronary artery bypass grafting. Few studies directly compared the clinical results of the radial artery ( RA ), right internal thoracic artery ( RITA ), and saphenous vein ( SV ). No network meta-analysis has compared these 3 strategies. Methods and Results MEDLINE and EMBASE were searched for adjusted observational studies and randomized controlled trials comparing the RA , SV , and/or RITA as the second conduit for coronary artery bypass grafting. The primary end point was all-cause long-term mortality. Secondary end points were operative mortality, perioperative stroke, perioperative myocardial infarction, and deep sternal wound infection ( DSWI ). Pairwise and network meta-analyses were performed. A total of 149 902 patients (4 randomized, 31 observational studies) were included ( RA , 16 201, SV , 112 018, RITA, 21 683). At NMA , the use of SV was associated with higher long-term mortality compared with the RA (incidence rate ratio, 1.23; 95% CI , 1.12-1.34) and RITA (incidence rate ratio, 1.26; 95% CI , 1.17-1.35). The risk of DSWI for SV was similar to RA but lower than RITA (odds ratio, 0.71; 95% CI , 0.55-0.91). There were no differences for any outcome between RITA and RA , although DSWI trended higher with RITA (odds ratio, 1.39; 95% CI , 0.92-2.1). The risk of DSWI in bilateral internal thoracic artery studies was higher when the skeletonization technique was not used. Conclusions The use of the RA or the RITA is associated with a similar and statistically significant long-term clinical benefit compared with the SV . There are no differences in operative risk or complications between the 2 arterial conduits, but DSWI remains a concern with bilateral ITA when skeletonization is not used.

Indexed as

Coronary Artery BypassCoronary Artery DiseaseHumansRadial ArterySaphenous Veinarterial conduitscoronary artery bypasscoronary artery bypass graft surgerysaphenous vein graft

Identifiers

PMID30636525
PMCPMC6497341
OpenAlexW2909164617

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.