ArticleDevelopmental period medicine
Prophphylactic bilateral salpingngectomy: why is it worthwhile?
Article in Developmental period medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Malignant tumors of the ovary are characterized by late detection which is the chief factor responsible for their poor prognosis. Almost 70% of ovarian cancers are diagnosed at clinical stage III or IV. At present, effective methods for early detection of ovarian cancer are lacking. One accepted approach to reduce the risk of ovarian cancer is bilateral salpingo-oophorectomy. However, it is increasingly widely believed that even a more limited surgery of bilateral salpingectomy may be also used prophylactically as an effective means to reduce cancer risk. The procedure is based on extensive anatomopathological research on the origins of malignant cells in ovarian cancer. There is already ample scientific evidence that in a high proportion of cases the primary site of neoplastic transformation is the distal segment of the fallopian tube, from which malignant cells migrate to the ovary. However, long-term studies demonstrating the effectiveness of prophylactic salpingectomy for ovarian cancer are required. This article summarizes the benefits and disadvantages of the procedure based on currently available literature.
Indexed as
Identifiers
30636239PMC8522816W3025631175What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.