Evidence map›Paper›PMID 30636174›Full record

ArticleClinical and experimental immunology2019

Vasoactive intestinal peptide is required in the maintenance of immune regulatory competency of immune regulatory monocytes.

L Guan, D Yu, G-H Wu, H-J Ning, S-D He, S-S Li, T-Y Hu, G Yang, Z-Q Liu, H-Q Yu and 3 more

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Clinical and experimental immunology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 53% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Regulatory Effects of CD14Journal of immunology research · 2026
    Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 1 institution in 1 country.

L GuanDepartment of Respirology, Third Affiliated Hospital of Shenzhen University, Shenzhen, China.
D YuResearch Center of Allergy and Immunology, Shenzhen University School of Medicine, Shenzhen, China.
G-H WuDepartment of Respirology, Third Affiliated Hospital of Shenzhen University, Shenzhen, China.
H-J NingResearch Center of Allergy and Immunology, Shenzhen University School of Medicine, Shenzhen, China.
S-D HeResearch Center of Allergy and Immunology, Shenzhen University School of Medicine, Shenzhen, China.
S-S LiResearch Center of Allergy and Immunology, Shenzhen University School of Medicine, Shenzhen, China.
T-Y HuResearch Center of Allergy and Immunology, Shenzhen University School of Medicine, Shenzhen, China.
G YangResearch Center of Allergy and Immunology, Shenzhen University School of Medicine, Shenzhen, China.
Z-Q LiuResearch Center of Allergy and Immunology, Shenzhen University School of Medicine, Shenzhen, China.
H-Q YuDepartment of Respirology, Third Affiliated Hospital of Shenzhen University, Shenzhen, China.
X-Z SunDepartment of Respirology, Third Affiliated Hospital of Shenzhen University, Shenzhen, China.
Z-G LiuResearch Center of Allergy and Immunology, Shenzhen University School of Medicine, Shenzhen, China.ORCID 0000-0002-8172-5120
P-C YangResearch Center of Allergy and Immunology, Shenzhen University School of Medicine, Shenzhen, China.ORCID 0000-0002-6806-9464
Shenzhen University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dysfunction of the immune regulatory system plays an important role in the pathogenesis of rheumatoid arthritis (RA). Vasoactive intestinal peptide (VIP) has multiple bioactivities. This study aims to investigate the role of VIP in the maintenance of the immune regulatory capacity of monocytes (Mos). Human peripheral blood samples were collected from RA patients and healthy control (HC) subjects. Mos and CD14

Indexed as

AdultAnimalsArthritis, RheumatoidCells, CulturedDisease Models, AnimalFemaleHumansImmunologic FactorsInterleukin-10MaleMonocytesRatsRats, Sprague-DawleyRNA, MessengerVasoactive Intestinal PeptideImmunologic FactorsInterleukin-10RNA, MessengerVasoactive Intestinal Peptideimmune regulationinflammationinterleukin-10monocytesrheumatoid arthritis

Identifiers

PMID30636174
PMCPMC6468183
OpenAlexW2910069311

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.