Evidence map›Paper›PMID 30635975›Full record

Observational studyCongenital heart disease2019

Feeding methods for infants with single ventricle physiology are associated with length of stay during stage 2 surgery hospitalization.

Jeannine M Hoch, Oluwatosin Fatusin, Gayane Yenokyan, W Reid Thompson, Maureen A Lefton-Greif

Open access · greenAbstract readComparative StudyObservational Study
In one paragraph

Observational study in Congenital heart disease, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Jeannine M HochDepartment of Pediatrics, Johns Hopkins Hospital, Baltimore, Maryland.
Oluwatosin FatusinDivision of Pediatric Cardiology, Department of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, Maryland.
Gayane YenokyanJohns Hopkins Biostatistics Center, Department of Biostatistics, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland.
W Reid ThompsonDivision of Pediatric Cardiology, Department of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, Maryland.
Maureen A Lefton-GreifDepartment of Pediatrics, Otolaryngology, Physical Medicine and Rehabilitation, Johns Hopkins University School of Medicine, Baltimore, Maryland.
Johns Hopkins Medicine · USJohns Hopkins University · USJohns Hopkins Hospital · US

Funding

Institute for Clinical and Translational ResearchUL1TR001079 · NCATS · JOHNS HOPKINS UNIVERSITY · PI FORD, DANIEL ERNEST · 2013 to 2017
$60.1M
Pursuing Perfection in Pediatric TheraputicsU19HS021114 · AHRQ · CINCINNATI CHILDRENS HOSP MED CTR · PI LANNON, CAROLE MARIE · 2011 to 2015
$4.2M
Training for Clinician Scientists in Pediatric Critical Cardiopulmonary DiseaseT32HL125239 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI BEMBEA, MELANIA MARIA, EVERETT, ALLEN D · 2015 to 2024
$3.0M
Agency for Healthcare Research and QualityAHRQ HHS U19 HS021114George Zoltan Lefton Family FoundationHayden Whitney Smith Family FoundationJohns Hopkins UniversityLazorchak Family FundNational Center for Advancing Translational SciencesNational Center for Research Resources 1UL1TR001079National Institutes of Health 1UL1TR001079NCATS NIH HHS UL1 TR001079NHLBI NIH HHS T32 HL125239School of Medicine
6 · The paper itself

Abstract

backgroundTube feedings are often needed to achieve the growth and nutrition goals associated with decreased morbidity and mortality in patients with single ventricle anatomy. Variability in feeding method through the interstage period has been previously described, however, comparable information following stage 2 palliation is lacking.

objectivesTo identify types of feeding methods following stage 2 palliation and their influence on length of stay.

designSecondary analysis of the National Pediatric Cardiology Quality Improvement Collaborative registry was performed on 932 patients. Demographic data, medical characteristics, postoperative complications, type of feeding method, and length of stay for stage 2 palliation were analyzed.

resultsType of feeding method remained relatively unchanged during hospitalization for stage 2 palliation. Gastrostomy tube fed only patients were the oldest at time of surgery (182.7 ± 57.7 days, P < .001) and had the lowest weight-for-age z scores at admission (-1.6 ± 1.4, P < .001). Oral + gastrostomy tube groups had the longest median bypass times (172.5 minutes, P = .001) and longest length of stay (median 12 days, P < .001). Multivariable modeling revealed that feeding by tube only (P < .001), oral + tube feeding (P ≤ .001), reintubation (P < .001), and prolonged intubation (P < .001) were associated with increased length of stay. Neither age (P = .156) nor weight-for-age z score at admission (P = .066) was predictive of length of stay.

conclusionsFeeding methods established at admission for stage 2 palliation are not likely to change by discharge. Length of stay is more likely to be impacted by tube feeding and intubation history than age or weight-for-age z score at admission. Better understanding for selection of feeding methods and their impact on patient outcomes is needed to develop evidence-based guidelines to decrease variability in clinical practice patterns and provide appropriate counseling to caregivers.

Indexed as

Cardiac Surgical ProceduresFeeding MethodsHospitalizationAge FactorsBottle FeedingChild DevelopmentEnteral NutritionFemaleGastrostomyHeart Defects, CongenitalHeart VentriclesHumansInfantInfant Nutritional Physiological PhenomenaLength of StayMaledeglutitionfeedinghypoplastic left heart syndromesingle ventriclestage 2 palliation

Identifiers

PMID30635975
PMCPMC6559846
OpenAlexW2908617241

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.