Evidence map›Paper›PMID 30635804›Full record

ReviewJournal of the Association for Research in Otolaryngology : JARO2019

Water Waves to Sound Waves: Using Zebrafish to Explore Hair Cell Biology.

Sarah B Pickett, David W Raible

Open access · bronzeAbstract readReview
In one paragraph

Review in Journal of the Association for Research in Otolaryngology : JARO, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed
3.7field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 65 citations in OpenAlex.

  1. Article
  2. Article
  3. Mutation of the GDP-Fucose Biosynthesis GeneInternational journal of molecular sciences · 2025
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Editorial: Views on JARO 2023.Journal of the Association for Research in Otolaryngology : JARO · 2024
    Article
  13. Hair Cell Regeneration: From Animals to Humans.Clinical and experimental otorhinolaryngology · 2024
    Review
  14. Article
  15. Article
  16. ZebrafishFrontiers in molecular neuroscience · 2024
    Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Sarah B PickettDepartment of Biological Structure, University of Washington, Health Sciences Building H-501, 1959 NE Pacific Street, Box 357420, Seattle, WA, 98195-7420, USA.
David W RaibleDepartment of Biological Structure, University of Washington, Health Sciences Building H-501, 1959 NE Pacific Street, Box 357420, Seattle, WA, 98195-7420, USA. draible@uw.edu.ORCID 0000-0002-5342-5841
Seattle Pacific University · USUniversity of Washington · US

Funding

Genetics of Zebrafish Hair Cell ToxicityR01DC005987 · NIDCD · UNIVERSITY OF WASHINGTON · PI RAIBLE, DAVID W · 2003 to 2023
$9.8M
Auditory Neuroscience Traning ProgramT32DC005361 · NIDCD · UNIVERSITY OF WASHINGTON · PI Adrian KC Lee, DAVID J PERKEL · 2002 to 2026
$8.8M
Mitochondrial function and dysfunction in hair cellsR01DC015783 · NIDCD · UNIVERSITY OF WASHINGTON · PI RAIBLE, DAVID W · 2017 to 2021
$1.6M
NIDCD NIH HHS R01 DC005987NIDCD NIH HHS R01 DC015783NIDCD NIH HHS T32 DC005361
6 · The paper itself

Abstract

Although perhaps best known for their use in developmental studies, over the last couple of decades, zebrafish have become increasingly popular model organisms for investigating auditory system function and disease. Like mammals, zebrafish possess inner ear mechanosensory hair cells required for hearing, as well as superficial hair cells of the lateral line sensory system, which mediate detection of directional water flow. Complementing mammalian studies, zebrafish have been used to gain significant insights into many facets of hair cell biology, including mechanotransduction and synaptic physiology as well as mechanisms of both hereditary and acquired hair cell dysfunction. Here, we provide an overview of this literature, highlighting some of the particular advantages of using zebrafish to investigate hearing and hearing loss.

Indexed as

AnimalsCell DeathCell PolarityEye ProteinsGlutaredoxinsHair Cells, AuditoryHearing LossMechanotransduction, CellularModels, AnimalMyosin VIIaSoundWaterZebrafishZebrafish Proteinsctbp2a protein, zebrafishEye ProteinsGlutaredoxinsgrxcr1b protein, zebrafishMyosin VIIaWaterZebrafish Proteinsauditory systemhearing losslateral line systemmechanosensation

Identifiers

PMID30635804
PMCPMC6364261
OpenAlexW2910290016

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.