Evidence map›Paper›PMID 30635708›Full record

ArticleEuropean journal of applied physiology2019

Heart rate recovery after maximal exercise is impaired in healthy young adults born preterm.

Kristin Haraldsdottir, Andrew M Watson, Arij G Beshish, Dave F Pegelow, Mari Palta, Laura H Tetri, Melissa D Brix, Ryan M Centanni, Kara N Goss, Marlowe W Eldridge

Open access · greenAbstract read
In one paragraph

Article in European journal of applied physiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed, 3 pooled it
5.2field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 3 syntheses or guidelines pooled it, 49 citations in OpenAlex.

  1. Physiological responses to exercise in survivors of preterm birth: a meta-analysis.European respiratory review : an official journal of the European Respiratory Society · 2025
    Pooled it
  2. A systematic review to investigate whether birth weight affects the autonomic nervous system in adulthood.Revista paulista de pediatria : orgao oficial da Sociedade de Pediatria de Sao Paulo · 2023
    Pooled it
  3. Pooled it
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  8. Cardiovascular Health Starts in the Womb.Hypertension (Dallas, Tex. : 1979) · 2024
    Review
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  20. Understanding the preterm human heart: What do we know so far?Anatomical record (Hoboken, N.J. : 2007) · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Kristin HaraldsdottirDepartment of Pediatrics, University of Wisconsin-Madison, Madison, WI, USA.ORCID http://orcid.org/0000-0002-9702-3430
Andrew M WatsonDepartment of Orthopedics and Rehabilitation, University of Wisconsin-Madison, 1685 Highland Avenue, UWMFCB-6130, Madison, WI, 53705, USA. watson@ortho.wisc.edu.
Arij G BeshishDepartment of Pediatrics, University of Wisconsin-Madison, Madison, WI, USA.
Dave F PegelowDepartment of Pediatrics, University of Wisconsin-Madison, Madison, WI, USA.
Mari PaltaDepartment of Biostatistics and Medical Informatics, University of Wisconsin-Madison, Madison, WI, USA.
Laura H TetriDepartment of Pediatrics, University of Wisconsin-Madison, Madison, WI, USA.
Melissa D BrixDepartment of Pediatrics, University of Wisconsin-Madison, Madison, WI, USA.
Ryan M CentanniDepartment of Pediatrics, University of Wisconsin-Madison, Madison, WI, USA.
Kara N GossDepartment of Pediatrics, University of Wisconsin-Madison, Madison, WI, USA.
Marlowe W EldridgeDepartment of Pediatrics, University of Wisconsin-Madison, Madison, WI, USA.
University of Wisconsin–Madison · US

Funding

Training Program in Translational Cardiovascular Science (TPTCS)T32HL007936 · NHLBI · UNIVERSITY OF WISCONSIN-MADISON · PI Lee Lochbaum Eckhardt, Gail A Robertson · 2001 to 2026
$11.6M
INTEGRATED TRAINING FOR PHYSICIAN-SCIENTISTST32GM008692 · NIGMS · UNIVERSITY OF WISCONSIN-MADISON · PI BURKARD, MARK E · 1998 to 2020
$10.3M
Right Heart-Pulmonary Vascular Interactions in Bronchopulmonary DysplasiaR01HL115061 · NHLBI · UNIVERSITY OF WISCONSIN-MADISON · PI ELDRIDGE, MARLOWE · 2012 to 2016
$3.2M
NHLBI NIH HHS R01 HL115061NHLBI NIH HHS T32 HL007936NIGMS NIH HHS T32 GM008692NIH HHS NIH-NHLBI R01-HL115061NIH HHS NIH-NHLBI R01Supplement-HL1150613NIH HHS T32-HL 07936
6 · The paper itself

Abstract

purposeThe long-term implications of premature birth on autonomic nervous system (ANS) function are unclear. Heart rate recovery (HRR) following maximal exercise is a simple tool to evaluate ANS function and is a strong predictor of cardiovascular disease. Our objective was to determine whether HRR is impaired in young adults born preterm (PYA).

methodsIndividuals born between 1989 and 1991 were recruited from the Newborn Lung Project, a prospectively followed cohort of subjects born preterm weighing < 1500 g with an average gestational age of 28 weeks. Age-matched term-born controls were recruited from the local population. HRR was measured for 2 min following maximal exercise testing on an upright cycle ergometer in normoxia and hypoxia, and maximal aerobic capacity (VO

resultsPreterms had lower VO

conclusionsAutonomic dysfunction as seen in this study has been associated with increased rates of cardiovascular disease in non-preterm populations, suggesting further study of the mechanisms of autonomic dysfunction after preterm birth.

Indexed as

Exercise TestAutonomic Nervous SystemErgometryExerciseExercise ToleranceFemaleHeart RateHumansHypoxiaInfant, NewbornMalePregnancyPremature BirthYoung AdultAutonomic dysfunctionAutonomic functionCardiovascular diseaseExercise testingHeart rate recoveryMaximal aerobic capacityPremature birthPrematurityPreterm birth

Identifiers

PMID30635708
PMCPMC7100254
OpenAlexW2910688705

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.