Evidence map›Paper›PMID 30635680›Full record

ArticlePsychopharmacology2019

The impact of Yohimbine-induced arousal on facets of behavioural impulsivity.

Aleksandra M Herman, Hugo D Critchley, Theodora Duka

Open access · hybridAbstract read
In one paragraph

Article in Psychopharmacology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 3 pooled it
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 3 syntheses or guidelines pooled it, 32 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Trial
  5. Effects of Acute Yohimbine Hydrochloride Supplementation on Repeated Supramaximal Sprint Performance.International journal of environmental research and public health · 2022
    Trial
  6. Review
  7. Review
  8. Multifaced Nature of Yohimbine-A Promising Therapeutic Potential or a Risk?International journal of molecular sciences · 2024
    Review
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Review
  17. Article
  18. Which came first: Cannabis use or deficits in impulse control?Progress in neuro-psychopharmacology & biological psychiatry · 2021
    Review
  19. Review
  20. Disentangling the effects of cannabis and cigarette smoking on impulsivity.Journal of psychopharmacology (Oxford, England) · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 1 country.

Aleksandra M HermanBehavioural and Clinical Neuroscience, School of Psychology, University of Sussex, Brighton, BN1 9QH, UK. a.herman@sussex.ac.uk.ORCID http://orcid.org/0000-0002-3338-0543
Hugo D CritchleySackler Centre for Consciousness Science, University of Sussex, Sussex, UK.
Theodora DukaBehavioural and Clinical Neuroscience, School of Psychology, University of Sussex, Brighton, BN1 9QH, UK.
Brighton and Sussex Medical School · GBEast Sussex County Council · GBUniversity of Sussex · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

rationaleState-dependent changes in physiological arousal may influence impulsive behaviours.

objectivesTo examine the relationship between arousal and impulsivity, we assessed the effects of yohimbine (an α

methodsForty-three participants received a single dose of either yohimbine hydrochloride or placebo before completing a battery of impulsivity measures. Blood pressure and heart rate were monitored throughout the study.

resultsParticipants in the yohimbine group showed higher blood pressure and better response inhibition in the Stop Signal Task, relative to the placebo group. Additionally, individual changes in blood pressure were associated with performance on Delay Discounting and Information Sampling tasks: raised blood pressure following drug ingestion was associated with more far-sighted decisions in the Delay Discounting Task (lower temporal impulsivity) yet reduced information gathering in the Information Sampling Task (increased reflection impulsivity).

conclusionsThese results support the notion that impulsive behaviour is dependent upon state physiological arousal; however, distinct facets of impulsivity are differentially affected by physiological changes.

Indexed as

Adrenergic alpha-2 Receptor AntagonistsAdultArousalDecision MakingDelay DiscountingFemaleHumansImpulsive BehaviorMalePsychomotor PerformanceYohimbineYoung AdultAdrenergic alpha-2 Receptor AntagonistsYohimbineBarratt Impulsiveness ScaleBlood pressureHeart rateNoradrenalineStop Signal TaskUPPS-PYohimbine

Identifiers

PMID30635680
PMCPMC6602985
OpenAlexW2908597287

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.