Evidence map›Paper›PMID 30635631›Full record

ArticleLeukemia2019

KIT D816 mutated/CBF-negative acute myeloid leukemia: a poor-risk subtype associated with systemic mastocytosis.

Mohamad Jawhar, Konstanze Döhner, Sebastian Kreil, Juliana Schwaab, Khalid Shoumariyeh, Manja Meggendorfer, Lambert L F Span, Stephan Fuhrmann, Nicole Naumann, Hans-Peter Horny and 16 more

Open access · hybridAbstract read
In one paragraph

Article in Leukemia, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 37 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Review
  6. Unraveling the Rare Entity ofJournal of hematology · 2024
    Article
  7. Review
  8. Article
  9. Review
  10. Article
  11. Article
  12. Therapy-related core binding factor acute myeloid leukemia.International journal of hematologic oncology · 2023
    Review
  13. Article
  14. Article
  15. Review
  16. Article
  17. Review
  18. Detection of the KITModern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc · 2020
    Article
  19. MARS: Mutation-Adjusted Risk Score for Advanced Systemic Mastocytosis.Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2019
    Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

26 authors at 13 institutions in 4 countries.

Mohamad JawharDepartment of Hematology and Oncology, University Hospital Mannheim, Heidelberg University, Mannheim, Germany.
Konstanze DöhnerDepartment of Internal Medicine III, University Hospital Ulm, Ulm, Germany.
Sebastian KreilDepartment of Hematology and Oncology, University Hospital Mannheim, Heidelberg University, Mannheim, Germany.
Juliana SchwaabDepartment of Hematology and Oncology, University Hospital Mannheim, Heidelberg University, Mannheim, Germany.
Khalid ShoumariyehDepartment of Hematology, Oncology and Stem Cell Transplantation, Medical Center, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Manja MeggendorferMunich Leukemia Laboratory, Munich, Germany.
Lambert L F SpanDepartment of Hematology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
Stephan FuhrmannDepartment of Hematology and Oncology, HELIOS Hospital, Berlin, Germany.
Nicole NaumannDepartment of Hematology and Oncology, University Hospital Mannheim, Heidelberg University, Mannheim, Germany.
Hans-Peter HornyInstitute of Pathology, Ludwig-Maximilians-University, Munich, Germany.
Karl SotlarInstitute of Pathology, Medical University of Salzburg, Salzburg, Austria.
Boris KubuschokDepartment of Internal Medicine I, José-Carreras Centrum for Immuno- and Gene Therapy, University of Saarland Medical School, Homburg/Saar, Germany.
Nikolas von BubnoffDepartment of Hematology, Oncology and Stem Cell Transplantation, Medical Center, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Karsten SpiekermannDepartment of Medicine III, University Hospital of Munich, Munich, Germany.
Michael HeuserDepartment of Hematology, Hemostasis, Oncology and Stem Cell Transplantation, Hannover Medical School, Hannover, Germany.
Georgia MetzgerothDepartment of Hematology and Oncology, University Hospital Mannheim, Heidelberg University, Mannheim, Germany.
Alice FabariusDepartment of Hematology and Oncology, University Hospital Mannheim, Heidelberg University, Mannheim, Germany.
Stefan KleinDepartment of Hematology and Oncology, University Hospital Mannheim, Heidelberg University, Mannheim, Germany.
Wolf-Karsten HofmannDepartment of Hematology and Oncology, University Hospital Mannheim, Heidelberg University, Mannheim, Germany.
Hanneke C Kluin-NelemansDepartment of Hematology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
Torsten HaferlachMunich Leukemia Laboratory, Munich, Germany.
Hartmut DöhnerDepartment of Internal Medicine III, University Hospital Ulm, Ulm, Germany.
Nicholas C P CrossWessex Regional Genetics Laboratory, Salisbury, UK.ORCID http://orcid.org/0000-0001-5481-2555
Wolfgang R SperrDepartment of Internal Medicine I, Division of Hematology and Ludwig Boltzmann Cluster Oncology, Medical University of Vienna, Vienna, Austria.
Peter ValentDepartment of Internal Medicine I, Division of Hematology and Ludwig Boltzmann Cluster Oncology, Medical University of Vienna, Vienna, Austria.
Andreas ReiterDepartment of Hematology and Oncology, University Hospital Mannheim, Heidelberg University, Mannheim, Germany. andreas.reiter@medma.uni-heidelberg.de.
Heidelberg University · DELudwig Boltzmann Institute for Cardiovascular Research · ATMunich Leukemia Laboratory (Germany) · DEUniversity Hospital Ulm · DEUniversity Medical Center Groningen · NLUniversity of Freiburg · DEHelios Hospital Berlin-Buch · DELMU Klinikum · DELudwig-Maximilians-Universität München · DEMedizinische Hochschule Hannover · DESaarland University · DEUniversity of Salzburg · ATWessex Regional Genetics Laboratory · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

KIT D816 mutations (KIT D816

Indexed as

AllelesMutationAdultAgedAged, 80 and overBiomarkersBone MarrowCore Binding FactorsCytogenetic AnalysisFemaleGene FrequencyHigh-Throughput Nucleotide SequencingHumansIn Situ Hybridization, FluorescenceKaplan-Meier EstimateLeukemia, Myeloid, AcuteBiomarkersCore Binding FactorsProto-Oncogene Proteins c-kit

Identifiers

PMID30635631
PMCPMC6756067
OpenAlexW2909944780

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.